Inhibiting synthesis of extracellular matrix improves patch clamp seal formation

The ability to form gigaohm seals is essential for patch-clamp studies. Cells with otherwise useful properties must be abandoned for electrophysiological studies if seal formation is not possible. We have found that by inhibiting the growth of extracellular matrix with beta-D-xyloside, the success o...

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Veröffentlicht in:	Pflügers Archiv 1991-09, Vol.419 (2), p.218-220
Hauptverfasser:	YE CHEN IZU, SACHS, F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Diverse techniques Electrophysiology - methods Extracellular Matrix - drug effects Fundamental and applied biological sciences. Psychology Glycosides - pharmacology Ion Channels Mice Molecular and cellular biology Tumor Cells, Cultured
Online-Zugang:	Volltext
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