Synthesis and Antitumor Activities of Novel Pyrimidine Derivatives of 2,3-O,O-Dibenzyl-6-deoxy-l-ascorbic Acid and 4,5-Didehydro-5,6- dideoxy-l-ascorbic Acid

The new pyrimidine derivatives of 2,3-O,O-dibenzyl-6-deoxy-l-ascorbic acid (8−10) were synthesized by condensation of uracil and its 5-fluoro- and 5-trifluoromethyl-substituted derivatives with 4-(5,6-epoxypropyl)-2,3-O,O-dibenzyl-l-ascorbic acid (7), while pyrimidine derivatives of 4,5-didehydro-5,...

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