Detection of anti-HIV antibodies in immunoglobulin preparations: the significance of antibodies to the HIV-envelope
Four hundred and sixty-eight immunoglobulin preparations, produced between 1969 and 1989, were examined for anti-HIV antibodies by means of two competitive immunoenzymatic assays and the Western blot test. This study refers the results obtained by the three different methods. Such results show that...
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| Veröffentlicht in: | Biologicals 1991-07, Vol.19 (3), p.197-202 |
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| container_title | Biologicals |
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| creator | Gentili, Giuliano Wlrz, Maria Puccinelli, Maria Mele, Claudio Collotti, Clelia Vicari, Gluseppe |
| description | Four hundred and sixty-eight immunoglobulin preparations, produced between 1969 and 1989, were examined for anti-HIV antibodies by means of two competitive immunoenzymatic assays and the Western blot test.
This study refers the results obtained by the three different methods. Such results show that the detection of anti-HIV antibodies in immunoglobulins may be performed on a routine basis using commercial kits intended for human sera.
The meaning of the test and the role of antibodies against the HIV envelope proteins are emphasized. |
| doi_str_mv | 10.1016/1045-1056(91)90035-I |
| format | Article |
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This study refers the results obtained by the three different methods. Such results show that the detection of anti-HIV antibodies in immunoglobulins may be performed on a routine basis using commercial kits intended for human sera.
The meaning of the test and the role of antibodies against the HIV envelope proteins are emphasized.</description><identifier>ISSN: 1045-1056</identifier><identifier>EISSN: 1095-8320</identifier><identifier>DOI: 10.1016/1045-1056(91)90035-I</identifier><identifier>PMID: 1954001</identifier><language>eng</language><publisher>Kent: Elsevier Ltd</publisher><subject>AIDS/HIV ; Biological and medical sciences ; Blotting, Western - statistics & numerical data ; Drug Contamination ; False Positive Reactions ; Fundamental and applied biological sciences. Psychology ; HIV Antibodies - isolation & purification ; HIV Antigens ; human immunodeficiency virus ; Humans ; Immunoenzyme Techniques - statistics & numerical data ; Immunoglobulins - isolation & purification ; Microbiology ; Safety ; Sensitivity and Specificity ; Viral Envelope Proteins - immunology ; Virology</subject><ispartof>Biologicals, 1991-07, Vol.19 (3), p.197-202</ispartof><rights>1991</rights><rights>1992 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c366t-542d03971d929eb9aa1adafb775fbb55dc70f8819a16fc6770e8355a2943d1363</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/104510569190035I$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=5261965$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1954001$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gentili, Giuliano</creatorcontrib><creatorcontrib>Wlrz, Maria</creatorcontrib><creatorcontrib>Puccinelli, Maria</creatorcontrib><creatorcontrib>Mele, Claudio</creatorcontrib><creatorcontrib>Collotti, Clelia</creatorcontrib><creatorcontrib>Vicari, Gluseppe</creatorcontrib><title>Detection of anti-HIV antibodies in immunoglobulin preparations: the significance of antibodies to the HIV-envelope</title><title>Biologicals</title><addtitle>Biologicals</addtitle><description>Four hundred and sixty-eight immunoglobulin preparations, produced between 1969 and 1989, were examined for anti-HIV antibodies by means of two competitive immunoenzymatic assays and the Western blot test.
This study refers the results obtained by the three different methods. Such results show that the detection of anti-HIV antibodies in immunoglobulins may be performed on a routine basis using commercial kits intended for human sera.
The meaning of the test and the role of antibodies against the HIV envelope proteins are emphasized.</description><subject>AIDS/HIV</subject><subject>Biological and medical sciences</subject><subject>Blotting, Western - statistics & numerical data</subject><subject>Drug Contamination</subject><subject>False Positive Reactions</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>HIV Antibodies - isolation & purification</subject><subject>HIV Antigens</subject><subject>human immunodeficiency virus</subject><subject>Humans</subject><subject>Immunoenzyme Techniques - statistics & numerical data</subject><subject>Immunoglobulins - isolation & purification</subject><subject>Microbiology</subject><subject>Safety</subject><subject>Sensitivity and Specificity</subject><subject>Viral Envelope Proteins - immunology</subject><subject>Virology</subject><issn>1045-1056</issn><issn>1095-8320</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUFv1TAQhC0EKqXwD0DKASF6SPEmthNzQEKlpU-qxAW4Wo69LkZJHOykUv89znuB3tqTd7XfjKwZQl4DPQMK4gNQxkugXLyXcCoprXm5e0KOgUpetnVFn67zhjwnL1L6TSkAa9gROQLJWd6OSfqCM5rZh7EIrtDj7Mur3c_90AXrMRV-LPwwLGO46UO39HmdIk466lWUPhbzLyySvxm980aPBv_5bPI57IlsWuJ4i32Y8CV55nSf8NX2npAflxffz6_K629fd-efr0tTCzGXnFWW1rIBKyuJndQatNWuaxruuo5zaxrq2hakBuGMaBqKbc25riSrLdSiPiHvDr5TDH8WTLMafDLY93rEsCTVVKxtKaseBUFUQracZpAdQBNDShGdmqIfdLxTQNVailoTV2viSoLal6J2WfZm81-6Ae296NBCvr_d7joZ3buYc_TpP8YrAVLwjH06YJhDu_UYVTIec-TWx9yhssE__I-_bhyorQ</recordid><startdate>19910701</startdate><enddate>19910701</enddate><creator>Gentili, Giuliano</creator><creator>Wlrz, Maria</creator><creator>Puccinelli, Maria</creator><creator>Mele, Claudio</creator><creator>Collotti, Clelia</creator><creator>Vicari, Gluseppe</creator><general>Elsevier Ltd</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>19910701</creationdate><title>Detection of anti-HIV antibodies in immunoglobulin preparations: the significance of antibodies to the HIV-envelope</title><author>Gentili, Giuliano ; Wlrz, Maria ; Puccinelli, Maria ; Mele, Claudio ; Collotti, Clelia ; Vicari, Gluseppe</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c366t-542d03971d929eb9aa1adafb775fbb55dc70f8819a16fc6770e8355a2943d1363</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1991</creationdate><topic>AIDS/HIV</topic><topic>Biological and medical sciences</topic><topic>Blotting, Western - statistics & numerical data</topic><topic>Drug Contamination</topic><topic>False Positive Reactions</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>HIV Antibodies - isolation & purification</topic><topic>HIV Antigens</topic><topic>human immunodeficiency virus</topic><topic>Humans</topic><topic>Immunoenzyme Techniques - statistics & numerical data</topic><topic>Immunoglobulins - isolation & purification</topic><topic>Microbiology</topic><topic>Safety</topic><topic>Sensitivity and Specificity</topic><topic>Viral Envelope Proteins - immunology</topic><topic>Virology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gentili, Giuliano</creatorcontrib><creatorcontrib>Wlrz, Maria</creatorcontrib><creatorcontrib>Puccinelli, Maria</creatorcontrib><creatorcontrib>Mele, Claudio</creatorcontrib><creatorcontrib>Collotti, Clelia</creatorcontrib><creatorcontrib>Vicari, Gluseppe</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Biologicals</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gentili, Giuliano</au><au>Wlrz, Maria</au><au>Puccinelli, Maria</au><au>Mele, Claudio</au><au>Collotti, Clelia</au><au>Vicari, Gluseppe</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Detection of anti-HIV antibodies in immunoglobulin preparations: the significance of antibodies to the HIV-envelope</atitle><jtitle>Biologicals</jtitle><addtitle>Biologicals</addtitle><date>1991-07-01</date><risdate>1991</risdate><volume>19</volume><issue>3</issue><spage>197</spage><epage>202</epage><pages>197-202</pages><issn>1045-1056</issn><eissn>1095-8320</eissn><abstract>Four hundred and sixty-eight immunoglobulin preparations, produced between 1969 and 1989, were examined for anti-HIV antibodies by means of two competitive immunoenzymatic assays and the Western blot test.
This study refers the results obtained by the three different methods. Such results show that the detection of anti-HIV antibodies in immunoglobulins may be performed on a routine basis using commercial kits intended for human sera.
The meaning of the test and the role of antibodies against the HIV envelope proteins are emphasized.</abstract><cop>Kent</cop><pub>Elsevier Ltd</pub><pmid>1954001</pmid><doi>10.1016/1045-1056(91)90035-I</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1045-1056 |
| ispartof | Biologicals, 1991-07, Vol.19 (3), p.197-202 |
| issn | 1045-1056 1095-8320 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | AIDS/HIV Biological and medical sciences Blotting, Western - statistics & numerical data Drug Contamination False Positive Reactions Fundamental and applied biological sciences. Psychology HIV Antibodies - isolation & purification HIV Antigens human immunodeficiency virus Humans Immunoenzyme Techniques - statistics & numerical data Immunoglobulins - isolation & purification Microbiology Safety Sensitivity and Specificity Viral Envelope Proteins - immunology Virology |
| title | Detection of anti-HIV antibodies in immunoglobulin preparations: the significance of antibodies to the HIV-envelope |
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