Quantitative Analysis of the Neuroendocrine–Immune Axis: Linear Modeling of the Effects of Exogenous Corticosterone and Restraint Stress on Lymphocyte Subpopulations in the Spleen and Thymus in Female B6C3F1 Mice

The effects of exogenous corticosterone and restraint stress on the number and percentage of lymphocyte subpopulations in the spleen and thymus were evaluated. The data were used to generate linear models that describe the relationship between these parameters and the area under the corticosterone c...

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Veröffentlicht in:	Brain, behavior, and immunity behavior, and immunity, 2000-12, Vol.14 (4), p.270-287
Hauptverfasser:	Pruett, Stephen B., Fan, Ruping, Myers, L.Peyton, Wu, Wen-Jun, Collier, Stephanie
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - pharmacology CD4-CD8 Ratio Corticosterone - pharmacology Female Key Words: corticosterone Linear Models lymphocyte Lymphocyte Subsets - drug effects Lymphocyte Subsets - immunology Mice Mice, Inbred C57BL modeling Neuroimmunomodulation - drug effects Neuroimmunomodulation - immunology restraint restraint stress Restraint, Physical spleen Spleen - cytology Spleen - immunology Stress, Physiological - immunology thymus Thymus Gland - cytology Thymus Gland - immunology
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