Effect of mycobacterial infection on virus loads and disease progression in simian immunodeficiency virus-infected rhesus monkeys

The effect of a mycobacterial infection on AIDS disease was studied in the simian model. Monkeys were infected with the primary virulent isolate SIV/DeltaB670 and inoculated 90 days later with BCG, an attenuated strain of Mycobacterium bovis. All monkeys experienced a dramatic transient increase in...

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Veröffentlicht in:	AIDS research and human retroviruses 2000-11, Vol.16 (17), p.1895-1908
Hauptverfasser:	CROIX, Denise A, CAPUANO, Saverio III, SIMPSON, Laura, FALLERT, Beth A, FULLER, Craig L, KLEIN, Edwin C, REINHART, Todd A, MURPHEY-CORB, Michael, FLYNN, Joanne L
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS-Related Opportunistic Infections - immunology AIDS-Related Opportunistic Infections - microbiology AIDS/HIV Animals Biological and medical sciences Disease Models, Animal Disease Progression Experimental viral diseases and models Fundamental and applied biological sciences. Psychology Human viral diseases Humans In Situ Hybridization Infectious diseases Lymph Nodes - virology Lymphocyte Activation Macaca mulatta Medical sciences Microbiology Mycobacterium bovis Mycobacterium bovis - immunology Receptors, CCR5 - metabolism RNA, Viral - blood Simian Acquired Immunodeficiency Syndrome - complications Simian Acquired Immunodeficiency Syndrome - physiopathology Simian immunodeficiency virus Simian Immunodeficiency Virus - physiology Spleen - virology Survivors T-Lymphocytes - immunology Tuberculosis - immunology Tuberculosis - microbiology Tuberculosis - physiopathology Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Viral Load virulence factors
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