Leukocyte elastase inhibition and t-PA-induced coronary artery thrombolysis in dogs: Beneficial effects on myocardial histology

Leukocyte-derived elastase is released following coronary artery occlusion and reperfusion and may contribute to reperfusion-related myocardial injury. Leukocyte infiltration into the reperfused myocardium may also contribute to ischemic injury following reflow. In the present study, we examined the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The American heart journal 1991-11, Vol.122 (5), p.1245-1251
Hauptverfasser:	Nicolini, F.A., Mehta, J.L., Nichols, W.W., Donnelly, W.H., Luostarinen, R., Saldeen, T.G.P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood. Blood coagulation. Reticuloendothelial system Coronary Thrombosis - blood Coronary Thrombosis - drug therapy Coronary Thrombosis - pathology Dogs Drug Evaluation, Preclinical Drug Therapy, Combination Heart - drug effects Leukocytes - drug effects Leukocytes - enzymology Medical sciences Myocardium - pathology Oligopeptides - therapeutic use Pancreatic Elastase - antagonists & inhibitors Pharmacology. Drug treatments Plasminogen Inactivators - blood Thrombolytic Therapy Tissue Plasminogen Activator - blood Tissue Plasminogen Activator - therapeutic use
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!