Insignificant transfer of glyburide occurs across the human placenta

No data exist concerning human placental transfer of oral hypoglycemic agents during pregnancy. This study characterizes the transport of glyburide in 10 term human placentas with the single-cotyledon placental model. Serial samples were taken from both the maternal and fetal reservoirs during each...

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Veröffentlicht in:	American journal of obstetrics and gynecology 1991-10, Vol.165 (4), p.807-812
Hauptverfasser:	Elliott, Byron D., Langer, Oded, Schenker, Steve, Johnson, Raymond F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences diazepam Diazepam - pharmacokinetics Female General and cellular metabolism. Vitamins Glyburide Glyburide - pharmacokinetics Humans Maternal-Fetal Exchange Medical sciences Models, Biological Pharmacology. Drug treatments placenta Placenta - metabolism Pregnancy pregnancy, human
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