Rhesus rotavirus-based quadrivalent vaccine is efficacious despite age, socioeconomic conditions and seasonality in Venezuela
This report describes the results of additional analyses of the trial carried out with the rhesus rotavirus-based quadrivalent vaccine in Venezuela. In the present study, we re-examined the data from this previous rotavirus vaccine trial to assess the statistical interaction between vaccine efficacy...
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| Veröffentlicht in: | Vaccine 2000-11, Vol.19 (7), p.976-981 |
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| container_issue | 7 |
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| container_title | Vaccine |
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| creator | Egleé Pérez, Marı́a Glass, Roger Alvarez, Giselle Pericchi, Luis Raúl González, Rosabel Kapikian, Albert Z. Pérez-Schael, Irene |
| description | This report describes the results of additional analyses of the trial carried out with the rhesus rotavirus-based quadrivalent vaccine in Venezuela. In the present study, we re-examined the data from this previous rotavirus vaccine trial to assess the statistical interaction between vaccine efficacy and (i) the duration of efficacy into the second year of life, (ii) socioeconomic conditions, and (iii) rotavirus seasonality. We found that among Venezuelan children, the rotavirus vaccine confers protection against severe diarrhea during the first 2 years of life independently of socioeconomic conditions and seasonality. |
| doi_str_mv | 10.1016/S0264-410X(00)00211-5 |
| format | Article |
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| source | MEDLINE; Elsevier ScienceDirect Journals; ProQuest Central UK/Ireland |
| subjects | Age Factors Animals Biological and medical sciences Diarrhea - epidemiology Diarrhea - prevention & control Double-Blind Method Efficacy Epidemiology. Vaccinations Female General aspects Humans Infant Infectious diseases Macaca mulatta Male Medical sciences Rotavirus Rotavirus - immunology Rotavirus Infections - epidemiology Rotavirus Infections - prevention & control Seasonality Seasons Socioeconomic Factors Socioeconomic status Vaccine Venezuela Venezuela - epidemiology Viral Vaccines - pharmacology |
| title | Rhesus rotavirus-based quadrivalent vaccine is efficacious despite age, socioeconomic conditions and seasonality in Venezuela |
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