Oxidative stress in patients with Friedreich ataxia

Increased generation of reactive oxygen species may underlie the pathophysiology of Friedreich ataxia (FRDA). The authors measured concentrations of 8-hydroxy-2'-deoxyguanosine (8OH2'dG), a marker of oxidative DNA damage, in urine and of dihydroxybenzoic acid (DHBA), a marker of hydroxyl r...

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Veröffentlicht in:	Neurology 2000-12, Vol.55 (11), p.1719-1721
Hauptverfasser:	SCHULZ, J. B, DEHMER, T, BOGDANOV, M. B, SCHÖLS, L, MENDE, H, HARDT, C, VORGERD, M, BÜRK, K, MATSON, W, DICHGANS, J, BEAL, M. F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Deoxyguanosine - analogs & derivatives Deoxyguanosine - urine Friedreich Ataxia - genetics Friedreich Ataxia - urine Humans Medical sciences Neurology Oxidative Stress
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