Acute antipsychotic drug administration lowers body temperature in drug-free male schizophrenic patients
We examined, in a controlled design, potential alterations in body temperature of male schizophrenic patients following acute antipsychotic drug (APD) administration. Fourteen drug-free (study group) and seven schizophrenic patients maintained on APDs (comparison group) initiated or received higher...
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Veröffentlicht in: | European neuropsychopharmacology 2000-12, Vol.10 (6), p.443-445 |
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creator | Shiloh, Roni Hermesh, Haggai Weizer, Nehama Dorfman-Etrog, Pnina Weizman, Abraham Munitz, Hanan |
description | We examined, in a controlled design, potential alterations in body temperature of male schizophrenic patients following acute antipsychotic drug (APD) administration. Fourteen drug-free (study group) and seven schizophrenic patients maintained on APDs (comparison group) initiated or received higher dose of their APD, respectively, for 27 days. Initial body temperature was 0.36°C higher in the study group (
P=0.01) and decreased within 24 h to values comparable to that of the comparison group (all within normal range). |
doi_str_mv | 10.1016/S0924-977X(00)00106-1 |
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Fourteen drug-free (study group) and seven schizophrenic patients maintained on APDs (comparison group) initiated or received higher dose of their APD, respectively, for 27 days. Initial body temperature was 0.36°C higher in the study group (
P=0.01) and decreased within 24 h to values comparable to that of the comparison group (all within normal range).</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>11115733</pmid><doi>10.1016/S0924-977X(00)00106-1</doi><tpages>3</tpages></addata></record> |
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subjects | Adolescent Adult Antipsychotic Agents - administration & dosage Antipsychotic Agents - pharmacology Antipsychotic Agents - therapeutic use Antipsychotic drugs Body temperature Body Temperature - drug effects Haloperidol - administration & dosage Haloperidol - pharmacology Haloperidol - therapeutic use Humans Longitudinal Studies Male Middle Aged Perphenazine - administration & dosage Perphenazine - pharmacology Perphenazine - therapeutic use Schizophrenia Schizophrenia - drug therapy Schizophrenia - physiopathology |
title | Acute antipsychotic drug administration lowers body temperature in drug-free male schizophrenic patients |
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