Regulation of N-methyl- d-aspartate receptor expression and N-methyl- d-aspartate-induced cellular response during chronic hypoxia in differentiated rat PC12 cells

The purpose of the present study was to examine the effect of chronic hypoxia on N-methyl- d-aspartate-mediated cellular responses in differentiated PC12 cells. PC12 cells were differentiated by treatment with nerve growth factor. Patch-clamp analysis in differentiated PC12 cells showed that extrace...

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Veröffentlicht in:	Neuroscience 2000, Vol.101 (4), p.1153-1162
Hauptverfasser:	Kobayashi, S, Millhorn, D.E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Differentiation, Myelomonocytic - pharmacology Biological and medical sciences Ca 2+ imaging Cell Differentiation Cell Survival Chronic Disease Fundamental and applied biological sciences. Psychology Hypoxia - metabolism Hypoxia - pathology Hypoxia - physiopathology hypoxic adaptation immunoblot Isolated neuron and nerve. Neuroglia Nerve Growth Factor - pharmacology northern blot patch-clamp PC12 Cells - drug effects PC12 Cells - metabolism PC12 Cells - pathology PC12 Cells - physiology Rats Receptors, N-Methyl-D-Aspartate - genetics Receptors, N-Methyl-D-Aspartate - metabolism RNA, Messenger - metabolism Transcription Factors - pharmacology Vertebrates: nervous system and sense organs
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