Bioavailability of ibuprofen from matrix mini-tablets based on a mixture of starch and microcrystalline wax

The bioavailability of ibuprofen from matrix mini-tablets based on microcrystalline wax and a starch derivative was tested. An oral dose of 300 mg of ibuprofen was administered to healthy volunteers ( n=8) in a randomized cross-over study design either as a commercial matrix formulation (Ibu-Slow ®...

Ausführliche Beschreibung