Identification of upstream stimulatory factor as an activator of the human dipeptidyl peptidase IV gene in Caco-2 cells

The 5′ upstream region (−448/−443) of the human dipeptidyl peptidase IV gene promoter containing a consensus E-box (CACGTG) was shown to bind upstream stimulatory factor using nuclear extracts from mouse (3T3) fibroblasts and the human intestinal and hepatic epithelial cell lines Caco-2 and HepG2. S...

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Veröffentlicht in:	Gene 2000-11, Vol.258 (1), p.77-84
Hauptverfasser:	Erickson, Roger H., Lai, Roy S., Lotterman, Craig D., Kim, Young S.
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Animals Base Sequence Binding Sites Caco-2 Cells Deoxyribonuclease I - metabolism Dipeptidyl Peptidase 4 - genetics Dipeptidyl Peptidase 4 - metabolism dipeptidyl peptidase IV DNA - genetics DNA - metabolism DNA Footprinting DNA, Recombinant DNA-Binding Proteins Gene promoter Humans Mice Molecular Sequence Data Peptidase Plasmids - genetics Promoter Regions, Genetic Protein Binding Small intestine Trans-Activators Transcription factors Transcription Factors - genetics Transcription Factors - metabolism Transfection Tumor Cells, Cultured Upstream Stimulatory Factors USF-1 protein USF-2 protein
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