Cloning and characterization of the genes encoding the ankyrin repeat and SOCS box-containing proteins Asb-1, Asb-2, Asb-3 and Asb-4

Members of the suppressor of cytokine signalling (SOCS) family of proteins have been shown to inhibit cytokine signalling via direct interactions with JAK kinases or activated cytokine receptors. In addition to their novel amino-terminal regions and SH2 domains that mediate these interactions, the S...

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Veröffentlicht in:	Gene 2000-11, Vol.258 (1), p.31-41
Hauptverfasser:	Kile, Benjamin T., Viney, Elizabeth M., Willson, Tracy A., Brodnicki, Thomas C., Cancilla, Michael R., Herlihy, Amy S., Croker, Ben A., Baca, Manuel, Nicola, Nicos A., Hilton, Douglas J., Alexander, Warren S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Ankyrin repeat Ankyrin Repeat - genetics Asb Asb-1 protein Asb-2 protein Asb-3 protein Asb-4 protein Base Sequence Blotting, Northern Carrier Proteins - genetics Chromosome Mapping Cloning, Molecular DNA - chemistry DNA - genetics DNA, Complementary - chemistry DNA, Complementary - genetics Exons Gene Expression Genes - genetics Humans Introns Male Mice Mice, Inbred C57BL Mice, Inbred Strains Molecular Sequence Data RNA, Messenger - genetics RNA, Messenger - metabolism Sequence Alignment Sequence Analysis, DNA Sequence Homology, Amino Acid SOCS suppressor of cytokine signalling protein Tissue Distribution
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