Modulation by pentobarbital of neutrophil responses to inhaled E. coli endotoxin in sheep: role of lung epithelium

Neutrophils (PMNs) are implicated in the pathogenesis of acute respiratory distress syndrome (ARDS). The role of the epithelium in the modulation of PMN migration within the lungs was examined. Epithelial integrity and PMN concentrations in the lung air spaces and lymph were measured in sheep anaest...

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Veröffentlicht in:	The European respiratory journal 2000-10, Vol.16 (4), p.697-703
Hauptverfasser:	Peterson, BT, Miller, EJ, Griffith, DE, Rowjee, R, McWaters, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Animals Bacterial diseases Bacterial diseases of the respiratory system Biological and medical sciences Bronchoalveolar Lavage Fluid - chemistry Endotoxins - administration & dosage Epithelium - drug effects Escherichia coli Human bacterial diseases Hypnotics and Sedatives - pharmacology Infectious diseases Interleukin-8 - analysis Lung - cytology Lung - drug effects Lymph - chemistry Medical sciences Neutrophils - drug effects Neutrophils - metabolism Pentobarbital - pharmacology Sheep Statistics, Nonparametric
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