Novel function for intestinal intraepithelial lymphocytes. Murine CD3+, gamma/delta TCR+ T cells produce IFN-gamma and IL-5

Intestinal intraepithelial lymphocytes (IEL) from mice are greater than 80% CD3+ T cells and could be separated into four subsets according to expression of CD4 and CD8. In our studies designed to assess the functions of IEL, namely, cytokine production, it was important to initially characterize th...

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Veröffentlicht in:	The Journal of immunology (1950) 1991-12, Vol.147 (11), p.3736-3744
Hauptverfasser:	Taguchi, T, Aicher, WK, Fujihashi, K, Yamamoto, M, McGhee, JR, Bluestone, JA, Kiyono, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Differentiation, T-Lymphocyte - analysis Antigens, Surface - analysis Biological and medical sciences CD3 Complex CD8 Antigens - analysis Epithelium - immunology Flow Cytometry Fundamental and applied biological sciences. Psychology Fundamental immunology Gene Expression Immunobiology Interferon-gamma - biosynthesis Interferon-gamma - genetics Interleukin-5 - biosynthesis Interleukin-5 - genetics Intestinal Mucosa - immunology Lymphoid cells: ontogeny, maturation, markers, receptors, circulation and recirculation Mice Mice, Inbred C3H Receptors, Antigen, T-Cell - analysis Receptors, Antigen, T-Cell, gamma-delta - analysis RNA, Messenger - genetics T-Lymphocyte Subsets - physiology Thy-1 Antigens
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