Expression of the human beta-amyloid protein of Alzheimer's disease specifically in the brains of transgenic mice

The human beta-amyloid protein is deposited in senile plaques and in the cerebro-vasculature of people with Alzheimer's disease and Down's syndrome. The precise role of beta-amyloid in Alzheimer's disease pathology is presently unknown. To study the properties of beta-amyloid in vivo,...

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Veröffentlicht in:The Journal of biological chemistry 1991-11, Vol.266 (32), p.21331-21334
Hauptverfasser: SANDHU, F. A, SALIM, M, ZAIN, S. B
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Sprache:eng
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