Covalent modification of guanine bases in double-stranded DNA. The 1.2-A Z-DNA structure of d(CGCGCG) in the presence of CuCl2

We have solved the single crystal structure to 1.2-A resolution of the Z-DNA sequence d(CGCGCG) soaked with copper(II) chloride. This structure allows us to elucidate the structural properties of copper in a model that mimics a physiologically relevant environment. A copper(II) cation was observed t...

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Veröffentlicht in:	The Journal of biological chemistry 1991-10, Vol.266 (30), p.20175-20184
Hauptverfasser:	Kagawa, T F, Geierstanger, B H, Wang, A H, Ho, P S
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Copper - metabolism Crystallization DNA - metabolism Guanine - metabolism Molecular Sequence Data
Online-Zugang:	Volltext
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