A Transgenic Approach to the Study of Peripheral T-Cell Tolerance

There is now convincing evidence for the imposition of self tolerance by means of the clonal deletion of self-reactive T cells operating within the thymus. Since not all self components may be encountered there, the question must be asked whether tolerance can occur post-thymically. To test this, we...

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Veröffentlicht in:	Immunological reviews 1991-08, Vol.122 (1), p.103-116
Hauptverfasser:	Miller, J. F. A. P., Morahan, G., Allison, J., Hoffmann, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autoimmunity - immunology Biological and medical sciences Fundamental and applied biological sciences. Psychology Fundamental immunology Histocompatibility Antigens Class I - immunology Immune Tolerance Immunobiology Immunological tolerance Interleukin-2 - immunology Mice Mice, Transgenic - immunology T-Lymphocytes - immunology
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