Nitric oxide synthetase inhibition hinders facilitation of active avoidance learning by nicotine in rats

Nicotine produces dose-dependent enhancement of performance in an active avoidance test, and also increases the levels of NO2 and NO3, which are stable metabolites of nitric oxide (NO), in various brain regions of rats. On the basis of these two observations, we hypothesized that the beneficial effe...

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Veröffentlicht in:	Behavioural pharmacology 2000-09, Vol.11 (6), p.505-510
Hauptverfasser:	Ylmaz, Ö, Kant, L, Okur, B.E, London, E.D, Pöğün, Ş
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Avoidance Learning - drug effects Enzyme Inhibitors - administration & dosage Enzyme Inhibitors - pharmacology Ganglionic Stimulants - pharmacology Male Nicotine - pharmacology Nitric Oxide - metabolism Nitric Oxide - pharmacology Nitric Oxide Synthase - metabolism Nitroarginine - administration & dosage Nitroarginine - pharmacology Rats Rats, Sprague-Dawley
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