Development of an in vitro model for cysteine dioxygenase expression in the brain

The development of an in vitro model for cysteine dioxygenase (CDO) expression in the brain would provide a useful model for determining the mechanisms for the regulation of CDO expression that does not involve the use of animals. Here we demonstrate the screening and characterization of a cell line...

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Veröffentlicht in:	Cell biology and toxicology 2000-01, Vol.16 (4), p.243-255
Hauptverfasser:	OUSTI, S, PARSONS, R. B, ABOUGLILA, K. D. H, WARING, R. H, WILLIAMS, A. C, RAMSDEN, D. B
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Animals Astrocytoma Base Sequence Biological and medical sciences Brain Brain - cytology Brain - enzymology Brain Neoplasms - enzymology Cell Survival Cerebellar Neoplasms Cysteine Dioxygenase Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Dioxygenases Enzymes Gene Expression Regulation, Enzymologic Glioblastoma Humans Male Medical sciences Medulloblastoma Models, Animal Models, Neurological Molecular Sequence Data Neurology Neurons - cytology Neurons - enzymology Oxygenases - genetics Parkinson's disease Pathology Polymerase chain reaction Rats Rats, Wistar Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - analysis Transcription, Genetic Tumor Cells, Cultured
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