Regulation of growth and apoptosis of cultured guinea pig gastric mucosal cells by mitogenic oxidase 1

We previously reported that primary cultures of guinea pig gastric pit cells expressed all of the phagocyte NADPH oxidase components (gp91-, p22-, p67-, p47-, and p40-phox) and could spontaneously release superoxide anion (O(2)(-)). We demonstrate here that pit cells express a nonphagocyte-specific...

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Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 2000-12, Vol.279 (6), p.G1169-G1176
Hauptverfasser:	Teshima, S, Kutsumi, H, Kawahara, T, Kishi, K, Rokutan, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - pharmacology Apoptosis - drug effects Caspases - metabolism Cells, Cultured Gastric Mucosa - enzymology Gastric Mucosa - growth & development Gastric Mucosa - physiology Guinea Pigs NADH, NADPH Oxidoreductases - biosynthesis NADH, NADPH Oxidoreductases - genetics NADH, NADPH Oxidoreductases - physiology NADPH Oxidases Neutrophils - metabolism NF-kappa B - metabolism Superoxides - metabolism Transcription, Genetic
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