CLIF, a Novel Cycle-like Factor, Regulates the Circadian Oscillation of Plasminogen Activator Inhibitor-1 Gene Expression

The onset of myocardial infarction occurs frequently in the early morning, and it may partly result from circadian variation of fibrinolytic activity. Plasminogen activator inhibitor-1 activity shows a circadian oscillation and may account for the morning onset of myocardial infarction. However, the...

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Veröffentlicht in:	The Journal of biological chemistry 2000-11, Vol.275 (47), p.36847-36851
Hauptverfasser:	Maemura, Koji, de la Monte, Suzanne M., Chin, Michael T., Layne, Matthew D., Hsieh, Chung-Ming, Yet, Shaw-Fang, Perrella, Mark A., Lee, Mu-En
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence ARNTL Transcription Factors Basic Helix-Loop-Helix Transcription Factors Circadian Rhythm CLIF protein CLOCK protein Cloning, Molecular Dimerization Gene Expression Regulation Helix-Loop-Helix Motifs Humans In Situ Hybridization Molecular Sequence Data myocardial infarction PAI-1 gene Phylogeny plasminogen activator inhibitor 1 Plasminogen Activator Inhibitor 1 - genetics Promoter Regions, Genetic Transcription Factors - genetics Transcription Factors - physiology Transcriptional Activation
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