An ex vivo angiogenesis assay utilizing commercial porcine carotid artery: Modification of the rat aortic ring assay

The study of angiogenesis as a therapeutic target requires a reliable, physiologically relevant, and technically straightforward assay. An ex vivo assay bridges the gap between cell-based assays, which may not realistically represent the complex process of vessel sprouting, and in vivo assays, which...

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Veröffentlicht in:	Angiogenesis (London) 2001, Vol.4 (1), p.3-9
Hauptverfasser:	STIFFEY-WILUSZ, Janet, BOICE, Judith A, RONAN, John, FLETCHER, Anthony M, ANDERSON, Matt S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta - drug effects Aorta - physiology Biological and medical sciences Biological Assay - methods Blood vessels and receptors Carotid Arteries - anatomy & histology Carotid Arteries - drug effects Carotid Arteries - growth & development Drug Evaluation, Preclinical Estradiol - analogs & derivatives Estradiol - pharmacology Fundamental and applied biological sciences. Psychology In Vitro Techniques Matrix Metalloproteinase Inhibitors Models, Cardiovascular Neovascularization, Physiologic - drug effects Phenylalanine - analogs & derivatives Phenylalanine - pharmacology Protease Inhibitors - pharmacology Rats Reproducibility of Results Suramin - pharmacology Swine Thiophenes - pharmacology Vertebrates: cardiovascular system
Online-Zugang:	Volltext
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