Marine n‐3 fatty acids: Basic features and background
There is some evidence from epidemiology that intake of n‐3 polyunsaturated fatty acids (PUFA) from seafood may protect against coronary artery disease (CAD). This hypothesis is further supported from animal data showing a beneficial effect of n‐3 PUFA on thrombosis and atherosclerosis in animals fe...
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| Veröffentlicht in: | Lipids 2001-01, Vol.36 (S1), p.S65-S68 |
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| container_title | Lipids |
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| creator | Schmidt, Erik Berg Christensen, Jeppe Hagstrup Aardestrup, Inge Madsen, Trine Riahi, Sam Hansen, Vibeke Ellegaard Skou, Helle Aarup |
| description | There is some evidence from epidemiology that intake of n‐3 polyunsaturated fatty acids (PUFA) from seafood may protect against coronary artery disease (CAD). This hypothesis is further supported from animal data showing a beneficial effect of n‐3 PUFA on thrombosis and atherosclerosis in animals fed fish oils in most, but not all, studies. There are several mechanisms by which an increased intake of marine n‐3 PUFA may protect against CAD; the most universal finding is a reduction of plasma triglycerides. It is puzzling, however, that a very low amount of n‐3 PUFA, with no known beneficial biochemical effects, seems to be cardioprotective. It has therefore been of paramount interest to perform clinical trials. Such evidence and trials are discussed in later chapters, and the results have been very encouraging. |
| doi_str_mv | 10.1007/s11745-001-0684-x |
| format | Article |
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This hypothesis is further supported from animal data showing a beneficial effect of n‐3 PUFA on thrombosis and atherosclerosis in animals fed fish oils in most, but not all, studies. There are several mechanisms by which an increased intake of marine n‐3 PUFA may protect against CAD; the most universal finding is a reduction of plasma triglycerides. It is puzzling, however, that a very low amount of n‐3 PUFA, with no known beneficial biochemical effects, seems to be cardioprotective. It has therefore been of paramount interest to perform clinical trials. Such evidence and trials are discussed in later chapters, and the results have been very encouraging.</description><identifier>ISSN: 0024-4201</identifier><identifier>EISSN: 1558-9307</identifier><identifier>DOI: 10.1007/s11745-001-0684-x</identifier><identifier>PMID: 11837995</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer‐Verlag</publisher><subject>Animals ; Arteriosclerosis - prevention & control ; Cardiovascular disease ; Coronary Disease - epidemiology ; Epidemiology ; Fatty acids ; Fatty Acids, Omega-3 - administration & dosage ; Fatty Acids, Omega-3 - adverse effects ; Fatty Acids, Omega-3 - chemistry ; Fish oils ; Fish Oils - administration & dosage ; Fishes ; Humans ; Nutrition ; Polyunsaturated fatty acids ; Risk Factors ; Seafood ; Thromboembolism ; Thrombosis - prevention & control ; Triglycerides - blood</subject><ispartof>Lipids, 2001-01, Vol.36 (S1), p.S65-S68</ispartof><rights>2001 American Oil Chemists' Society (AOCS)</rights><rights>AOCS Press 2001</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3715-72a0ff2d404461a0ee965a218c34630b2ce44dc8f42b600041bb9fb48e5aafae3</citedby><cites>FETCH-LOGICAL-c3715-72a0ff2d404461a0ee965a218c34630b2ce44dc8f42b600041bb9fb48e5aafae3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1007%2Fs11745-001-0684-x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1007%2Fs11745-001-0684-x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,4009,27902,27903,27904,45553,45554</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11837995$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schmidt, Erik Berg</creatorcontrib><creatorcontrib>Christensen, Jeppe Hagstrup</creatorcontrib><creatorcontrib>Aardestrup, Inge</creatorcontrib><creatorcontrib>Madsen, Trine</creatorcontrib><creatorcontrib>Riahi, Sam</creatorcontrib><creatorcontrib>Hansen, Vibeke Ellegaard</creatorcontrib><creatorcontrib>Skou, Helle Aarup</creatorcontrib><title>Marine n‐3 fatty acids: Basic features and background</title><title>Lipids</title><addtitle>Lipids</addtitle><description>There is some evidence from epidemiology that intake of n‐3 polyunsaturated fatty acids (PUFA) from seafood may protect against coronary artery disease (CAD). 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Academic</collection><jtitle>Lipids</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schmidt, Erik Berg</au><au>Christensen, Jeppe Hagstrup</au><au>Aardestrup, Inge</au><au>Madsen, Trine</au><au>Riahi, Sam</au><au>Hansen, Vibeke Ellegaard</au><au>Skou, Helle Aarup</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Marine n‐3 fatty acids: Basic features and background</atitle><jtitle>Lipids</jtitle><addtitle>Lipids</addtitle><date>2001-01</date><risdate>2001</risdate><volume>36</volume><issue>S1</issue><spage>S65</spage><epage>S68</epage><pages>S65-S68</pages><issn>0024-4201</issn><eissn>1558-9307</eissn><abstract>There is some evidence from epidemiology that intake of n‐3 polyunsaturated fatty acids (PUFA) from seafood may protect against coronary artery disease (CAD). This hypothesis is further supported from animal data showing a beneficial effect of n‐3 PUFA on thrombosis and atherosclerosis in animals fed fish oils in most, but not all, studies. There are several mechanisms by which an increased intake of marine n‐3 PUFA may protect against CAD; the most universal finding is a reduction of plasma triglycerides. It is puzzling, however, that a very low amount of n‐3 PUFA, with no known beneficial biochemical effects, seems to be cardioprotective. It has therefore been of paramount interest to perform clinical trials. Such evidence and trials are discussed in later chapters, and the results have been very encouraging.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer‐Verlag</pub><pmid>11837995</pmid><doi>10.1007/s11745-001-0684-x</doi><tpages>4</tpages></addata></record> |
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| subjects | Animals Arteriosclerosis - prevention & control Cardiovascular disease Coronary Disease - epidemiology Epidemiology Fatty acids Fatty Acids, Omega-3 - administration & dosage Fatty Acids, Omega-3 - adverse effects Fatty Acids, Omega-3 - chemistry Fish oils Fish Oils - administration & dosage Fishes Humans Nutrition Polyunsaturated fatty acids Risk Factors Seafood Thromboembolism Thrombosis - prevention & control Triglycerides - blood |
| title | Marine n‐3 fatty acids: Basic features and background |
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