Mutational and comparative analysis of streptolysin O, an oxygen-labile streptococcal hemolysin

The structural gene of streptolysin O was cloned from Streptococcus pyogenes strain Sa and S. equisimilis H46A, and the nucleotide sequences were compared with those of strain Richards. To obtain the minimal active fragment of the toxin and to elucidate structure-function relationships in hemolytic...

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Veröffentlicht in:	Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2001-12, Vol.65 (12), p.2682-2689
Hauptverfasser:	Yamamoto, I. (Fukui Medical School, Matsuoka (Japan)), Kimoto, H, Taketo, Y, Taketo, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Bacterial Proteins Base Sequence Biological and medical sciences Biotechnology DNA Primers Fundamental and applied biological sciences. Psychology GENES Genes, Bacterial HAEMOLYSIS hemolysin Hemolysin Proteins - metabolism MOLECULAR CLONING Molecular Sequence Data MUTATION mutational analysis NUCLEOTIDE SEQUENCE Oxygen - metabolism Plasmids Point Mutation Sheep STREPTOCOCCUS Streptococcus pyogenes - genetics Streptococcus pyogenes - metabolism streptolysin O Streptolysins - chemistry Streptolysins - genetics Streptolysins - metabolism
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