Analysis of Mouse Keratin 6a Regulatory Sequences in Transgenic Mice Reveals Constitutive, Tissue-Specific Expression by a Keratin 6a Minigene

The analysis of keratin 6 expression is complicated by the presence of multiple isoforms that are expressed constitutively in a number of internal stratified epithelia, in palmoplantar epidermis, and in the companion cell layer of the hair follicle. In addition, keratin 6 expression is inducible in...

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Veröffentlicht in:	Journal of investigative dermatology 2000-11, Vol.115 (5), p.795-804
Hauptverfasser:	Mahony, Donna, Karunaratne, Seetha, Rothnagel, Joseph A., Cam, Graham
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cells, Cultured Dermatology Fluorescent Antibody Technique, Direct Gene Expression gene regulation Investigative techniques, diagnostic techniques (general aspects) Keratinocytes - metabolism Keratins - genetics Lac Operon - physiology Medical sciences Mice Mice, Transgenic - genetics Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques promoter analysis Regulatory Sequences, Nucleic Acid Tissue Distribution Transgenes - physiology β-galactosidase
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