Aerobic Conditioning in Mild Asthma Decreases the Hyperpnea of Exercise and Improves Exercise and Ventilatory Capacity
To determine the effect of an aerobicconditioning program on fitness, respiratory physiology, and restinglung function in patients with mild asthma. Prospective cohort study. Outpatientrehabilitation facility. Five patients withmild intermittent asthma and five normal control subjects completed a10-...
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| Veröffentlicht in: | Chest 2000-11, Vol.118 (5), p.1460-1469 |
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| description | To determine the effect of an aerobicconditioning program on fitness, respiratory physiology, and restinglung function in patients with mild asthma.
Prospective cohort study.
Outpatientrehabilitation facility.
Five patients withmild intermittent asthma and five normal control subjects completed a10-week aerobic conditioning program. Pulmonary function studies andnoninvasive cardiopulmonary exercise tests were performed before andafter the conditioning program.
After aerobicconditioning, there were significant gains in maximum oxygenconsumption ( V˙o2max; 22.73 mL/kg/min vs25.29 mL/kg/min, p = 0.01, asthma; 22.94 mL/kg/min vs 27.85mL/kg/min, p = 0.03, control) and anaerobic threshold (0.99 L/min vs1.09 L/min, p = 0.03, asthma; 0.89 L/min vs 1.13 L/min, p = 0.01,control) in both groups. Although FEV1 was unchanged, themaximum voluntary ventilation (MVV) improved in the asthma group (96.0L/min vs 108.2 L/min, p = 0.08, asthma; 134.0 L/min vs 131.2 L/min,p = 0.35, control). During exercise, minute ventilation( V˙e) for each level of work was decreased in theasthma group after conditioning, while little change occurred in thecontrol group (68.48 L/min vs 51.70 L/min at initial V˙o2max, p = 0.02, asthma; 65.82 L/minvs 63.12 L/min at initial V˙o2max,p = 0.60, control). A significant decrease in the ventilatoryequivalent ( V˙e/oxygen consumption, 40.8 vs 30.4 at V˙o2max, p = 0.02, asthma; 37.2 vs 35.84 at V˙o2max, p = 0.02,control) and the dyspnea index ( V˙e/MVV) at submaximal(0.44 vs 0.38, p = 0.05, asthma; 0.32 vs 0.38, p < 0.01, control)and maximal exercise (0.72 vs 0.63, p = 0.03, asthma; 0.49 vs 0.62,p = 0.02, control) occurred in the asthma group.
Exercise rehabilitation improves aerobicfitness in both asthmatic and nonasthmatic participants of a 10-weekaerobic fitness program. Additional benefits of improved ventilatorycapacity and decreased hyperpnea of exercise occurred in patients withmild asthma. |
| doi_str_mv | 10.1378/chest.118.5.1460 |
| format | Article |
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Prospective cohort study.
Outpatientrehabilitation facility.
Five patients withmild intermittent asthma and five normal control subjects completed a10-week aerobic conditioning program. Pulmonary function studies andnoninvasive cardiopulmonary exercise tests were performed before andafter the conditioning program.
After aerobicconditioning, there were significant gains in maximum oxygenconsumption ( V˙o2max; 22.73 mL/kg/min vs25.29 mL/kg/min, p = 0.01, asthma; 22.94 mL/kg/min vs 27.85mL/kg/min, p = 0.03, control) and anaerobic threshold (0.99 L/min vs1.09 L/min, p = 0.03, asthma; 0.89 L/min vs 1.13 L/min, p = 0.01,control) in both groups. Although FEV1 was unchanged, themaximum voluntary ventilation (MVV) improved in the asthma group (96.0L/min vs 108.2 L/min, p = 0.08, asthma; 134.0 L/min vs 131.2 L/min,p = 0.35, control). During exercise, minute ventilation( V˙e) for each level of work was decreased in theasthma group after conditioning, while little change occurred in thecontrol group (68.48 L/min vs 51.70 L/min at initial V˙o2max, p = 0.02, asthma; 65.82 L/minvs 63.12 L/min at initial V˙o2max,p = 0.60, control). A significant decrease in the ventilatoryequivalent ( V˙e/oxygen consumption, 40.8 vs 30.4 at V˙o2max, p = 0.02, asthma; 37.2 vs 35.84 at V˙o2max, p = 0.02,control) and the dyspnea index ( V˙e/MVV) at submaximal(0.44 vs 0.38, p = 0.05, asthma; 0.32 vs 0.38, p < 0.01, control)and maximal exercise (0.72 vs 0.63, p = 0.03, asthma; 0.49 vs 0.62,p = 0.02, control) occurred in the asthma group.
Exercise rehabilitation improves aerobicfitness in both asthmatic and nonasthmatic participants of a 10-weekaerobic fitness program. Additional benefits of improved ventilatorycapacity and decreased hyperpnea of exercise occurred in patients withmild asthma.</description><identifier>ISSN: 0012-3692</identifier><identifier>EISSN: 1931-3543</identifier><identifier>DOI: 10.1378/chest.118.5.1460</identifier><identifier>PMID: 11083702</identifier><identifier>CODEN: CHETBF</identifier><language>eng</language><publisher>Northbrook, IL: Elsevier Inc</publisher><subject>Adult ; Anaerobic Threshold - physiology ; asthma ; Asthma - physiopathology ; Asthma - rehabilitation ; Biological and medical sciences ; Carbon Dioxide - metabolism ; Cohort Studies ; Diseases of the respiratory system ; Dyspnea - physiopathology ; Dyspnea - prevention & control ; Exercise - physiology ; Exercise Test ; Exercise Tolerance - physiology ; exercise-induced bronchospasm ; Female ; Forced Expiratory Volume - physiology ; Humans ; Hyperventilation - prevention & control ; Lung - physiopathology ; Male ; Maximal Voluntary Ventilation - physiology ; Medical sciences ; Oxygen Consumption - physiology ; Partial Pressure ; Physical Fitness - physiology ; Prospective Studies ; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) ; rehabilitation ; Respiratory Dead Space - physiology ; Respiratory Physiological Phenomena ; Tidal Volume - physiology</subject><ispartof>Chest, 2000-11, Vol.118 (5), p.1460-1469</ispartof><rights>2000 The American College of Chest Physicians</rights><rights>2001 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c415t-5fbdfee9dfabbec4ac47c03d9149f7d5388d38dcc1f05003548b58a1dffcb65c3</citedby><cites>FETCH-LOGICAL-c415t-5fbdfee9dfabbec4ac47c03d9149f7d5388d38dcc1f05003548b58a1dffcb65c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=803132$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11083702$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hallstrand, Teal S.</creatorcontrib><creatorcontrib>Bates, Peter W.</creatorcontrib><creatorcontrib>Schoene, Robert B.</creatorcontrib><title>Aerobic Conditioning in Mild Asthma Decreases the Hyperpnea of Exercise and Improves Exercise and Ventilatory Capacity</title><title>Chest</title><addtitle>Chest</addtitle><description>To determine the effect of an aerobicconditioning program on fitness, respiratory physiology, and restinglung function in patients with mild asthma.
Prospective cohort study.
Outpatientrehabilitation facility.
Five patients withmild intermittent asthma and five normal control subjects completed a10-week aerobic conditioning program. Pulmonary function studies andnoninvasive cardiopulmonary exercise tests were performed before andafter the conditioning program.
After aerobicconditioning, there were significant gains in maximum oxygenconsumption ( V˙o2max; 22.73 mL/kg/min vs25.29 mL/kg/min, p = 0.01, asthma; 22.94 mL/kg/min vs 27.85mL/kg/min, p = 0.03, control) and anaerobic threshold (0.99 L/min vs1.09 L/min, p = 0.03, asthma; 0.89 L/min vs 1.13 L/min, p = 0.01,control) in both groups. Although FEV1 was unchanged, themaximum voluntary ventilation (MVV) improved in the asthma group (96.0L/min vs 108.2 L/min, p = 0.08, asthma; 134.0 L/min vs 131.2 L/min,p = 0.35, control). During exercise, minute ventilation( V˙e) for each level of work was decreased in theasthma group after conditioning, while little change occurred in thecontrol group (68.48 L/min vs 51.70 L/min at initial V˙o2max, p = 0.02, asthma; 65.82 L/minvs 63.12 L/min at initial V˙o2max,p = 0.60, control). A significant decrease in the ventilatoryequivalent ( V˙e/oxygen consumption, 40.8 vs 30.4 at V˙o2max, p = 0.02, asthma; 37.2 vs 35.84 at V˙o2max, p = 0.02,control) and the dyspnea index ( V˙e/MVV) at submaximal(0.44 vs 0.38, p = 0.05, asthma; 0.32 vs 0.38, p < 0.01, control)and maximal exercise (0.72 vs 0.63, p = 0.03, asthma; 0.49 vs 0.62,p = 0.02, control) occurred in the asthma group.
Exercise rehabilitation improves aerobicfitness in both asthmatic and nonasthmatic participants of a 10-weekaerobic fitness program. Additional benefits of improved ventilatorycapacity and decreased hyperpnea of exercise occurred in patients withmild asthma.</description><subject>Adult</subject><subject>Anaerobic Threshold - physiology</subject><subject>asthma</subject><subject>Asthma - physiopathology</subject><subject>Asthma - rehabilitation</subject><subject>Biological and medical sciences</subject><subject>Carbon Dioxide - metabolism</subject><subject>Cohort Studies</subject><subject>Diseases of the respiratory system</subject><subject>Dyspnea - physiopathology</subject><subject>Dyspnea - prevention & control</subject><subject>Exercise - physiology</subject><subject>Exercise Test</subject><subject>Exercise Tolerance - physiology</subject><subject>exercise-induced bronchospasm</subject><subject>Female</subject><subject>Forced Expiratory Volume - physiology</subject><subject>Humans</subject><subject>Hyperventilation - prevention & control</subject><subject>Lung - physiopathology</subject><subject>Male</subject><subject>Maximal Voluntary Ventilation - physiology</subject><subject>Medical sciences</subject><subject>Oxygen Consumption - physiology</subject><subject>Partial Pressure</subject><subject>Physical Fitness - physiology</subject><subject>Prospective Studies</subject><subject>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</subject><subject>rehabilitation</subject><subject>Respiratory Dead Space - physiology</subject><subject>Respiratory Physiological Phenomena</subject><subject>Tidal Volume - physiology</subject><issn>0012-3692</issn><issn>1931-3543</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kM9vFCEYhonR2G317smQmHibFYb56W2zVtukxot6JczHR4eGgRFmV_e_l3Y3Nj14IpDnfb-Ph5A3nK25aLsPMGJa1px363rNq4Y9IyveC16IuhLPyYoxXhai6cszcp7SHct33jcvyRnnrBMtK1dkv8EYBgt0G7y2iw3e-ltqPf1qnaabtIyTop8QIqqEiS4j0qvDjHH2qGgw9PIPRrAJqfKaXk9zDPuMPXn9iX6xTi0hHuhWzQrscnhFXhjlEr4-nRfkx-fL79ur4ubbl-vt5qaAitdLUZtBG8ReGzUMCJWCqgUmdM-r3rS6Fl2nRacBuGE1Y_nb3VB3imtjYGhqEBfk_bE3L_Zrl2XJySZA55THsEuyLSve91WTQXYEIYaUIho5RzupeJCcyXvX8sG1zK5lLe9d58jbU_dumFA_Bk5yM_DuBKgEypmofJbyj-uY4KJ8nDza2_G3jSjTpJzLpeI48y7solfuyeSPxwhmdXuLUSaw6AF1jsMidbD_X_svP5Svbg</recordid><startdate>20001101</startdate><enddate>20001101</enddate><creator>Hallstrand, Teal S.</creator><creator>Bates, Peter W.</creator><creator>Schoene, Robert B.</creator><general>Elsevier Inc</general><general>American College of Chest Physicians</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20001101</creationdate><title>Aerobic Conditioning in Mild Asthma Decreases the Hyperpnea of Exercise and Improves Exercise and Ventilatory Capacity</title><author>Hallstrand, Teal S. ; Bates, Peter W. ; Schoene, Robert B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c415t-5fbdfee9dfabbec4ac47c03d9149f7d5388d38dcc1f05003548b58a1dffcb65c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Adult</topic><topic>Anaerobic Threshold - physiology</topic><topic>asthma</topic><topic>Asthma - physiopathology</topic><topic>Asthma - rehabilitation</topic><topic>Biological and medical sciences</topic><topic>Carbon Dioxide - metabolism</topic><topic>Cohort Studies</topic><topic>Diseases of the respiratory system</topic><topic>Dyspnea - physiopathology</topic><topic>Dyspnea - prevention & control</topic><topic>Exercise - physiology</topic><topic>Exercise Test</topic><topic>Exercise Tolerance - physiology</topic><topic>exercise-induced bronchospasm</topic><topic>Female</topic><topic>Forced Expiratory Volume - physiology</topic><topic>Humans</topic><topic>Hyperventilation - prevention & control</topic><topic>Lung - physiopathology</topic><topic>Male</topic><topic>Maximal Voluntary Ventilation - physiology</topic><topic>Medical sciences</topic><topic>Oxygen Consumption - physiology</topic><topic>Partial Pressure</topic><topic>Physical Fitness - physiology</topic><topic>Prospective Studies</topic><topic>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</topic><topic>rehabilitation</topic><topic>Respiratory Dead Space - physiology</topic><topic>Respiratory Physiological Phenomena</topic><topic>Tidal Volume - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hallstrand, Teal S.</creatorcontrib><creatorcontrib>Bates, Peter W.</creatorcontrib><creatorcontrib>Schoene, Robert B.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Chest</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hallstrand, Teal S.</au><au>Bates, Peter W.</au><au>Schoene, Robert B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Aerobic Conditioning in Mild Asthma Decreases the Hyperpnea of Exercise and Improves Exercise and Ventilatory Capacity</atitle><jtitle>Chest</jtitle><addtitle>Chest</addtitle><date>2000-11-01</date><risdate>2000</risdate><volume>118</volume><issue>5</issue><spage>1460</spage><epage>1469</epage><pages>1460-1469</pages><issn>0012-3692</issn><eissn>1931-3543</eissn><coden>CHETBF</coden><abstract>To determine the effect of an aerobicconditioning program on fitness, respiratory physiology, and restinglung function in patients with mild asthma.
Prospective cohort study.
Outpatientrehabilitation facility.
Five patients withmild intermittent asthma and five normal control subjects completed a10-week aerobic conditioning program. Pulmonary function studies andnoninvasive cardiopulmonary exercise tests were performed before andafter the conditioning program.
After aerobicconditioning, there were significant gains in maximum oxygenconsumption ( V˙o2max; 22.73 mL/kg/min vs25.29 mL/kg/min, p = 0.01, asthma; 22.94 mL/kg/min vs 27.85mL/kg/min, p = 0.03, control) and anaerobic threshold (0.99 L/min vs1.09 L/min, p = 0.03, asthma; 0.89 L/min vs 1.13 L/min, p = 0.01,control) in both groups. Although FEV1 was unchanged, themaximum voluntary ventilation (MVV) improved in the asthma group (96.0L/min vs 108.2 L/min, p = 0.08, asthma; 134.0 L/min vs 131.2 L/min,p = 0.35, control). During exercise, minute ventilation( V˙e) for each level of work was decreased in theasthma group after conditioning, while little change occurred in thecontrol group (68.48 L/min vs 51.70 L/min at initial V˙o2max, p = 0.02, asthma; 65.82 L/minvs 63.12 L/min at initial V˙o2max,p = 0.60, control). A significant decrease in the ventilatoryequivalent ( V˙e/oxygen consumption, 40.8 vs 30.4 at V˙o2max, p = 0.02, asthma; 37.2 vs 35.84 at V˙o2max, p = 0.02,control) and the dyspnea index ( V˙e/MVV) at submaximal(0.44 vs 0.38, p = 0.05, asthma; 0.32 vs 0.38, p < 0.01, control)and maximal exercise (0.72 vs 0.63, p = 0.03, asthma; 0.49 vs 0.62,p = 0.02, control) occurred in the asthma group.
Exercise rehabilitation improves aerobicfitness in both asthmatic and nonasthmatic participants of a 10-weekaerobic fitness program. Additional benefits of improved ventilatorycapacity and decreased hyperpnea of exercise occurred in patients withmild asthma.</abstract><cop>Northbrook, IL</cop><pub>Elsevier Inc</pub><pmid>11083702</pmid><doi>10.1378/chest.118.5.1460</doi><tpages>10</tpages></addata></record> |
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| subjects | Adult Anaerobic Threshold - physiology asthma Asthma - physiopathology Asthma - rehabilitation Biological and medical sciences Carbon Dioxide - metabolism Cohort Studies Diseases of the respiratory system Dyspnea - physiopathology Dyspnea - prevention & control Exercise - physiology Exercise Test Exercise Tolerance - physiology exercise-induced bronchospasm Female Forced Expiratory Volume - physiology Humans Hyperventilation - prevention & control Lung - physiopathology Male Maximal Voluntary Ventilation - physiology Medical sciences Oxygen Consumption - physiology Partial Pressure Physical Fitness - physiology Prospective Studies Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) rehabilitation Respiratory Dead Space - physiology Respiratory Physiological Phenomena Tidal Volume - physiology |
| title | Aerobic Conditioning in Mild Asthma Decreases the Hyperpnea of Exercise and Improves Exercise and Ventilatory Capacity |
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