Signalling aspects of insulin resistance in skeletal muscle: mechanisms induced by lipid oversupply

A reduced capacity for insulin to elicit increases in glucose uptake and metabolism in target tissues such as skeletal muscle is a common feature of obesity and diabetes. The association between lipid oversupply and such insulin resistance is well established, and evidence for mechanisms through whi...

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Veröffentlicht in:	Cellular Signalling 2000-10, Vol.12 (9), p.583-594
1. Verfasser:	Schmitz-Peiffer, Carsten
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Ceramide Diacylglycerol Glucose - metabolism Hexosamine Humans Insulin Resistance Lipid Metabolism Lipids Muscle, Skeletal - metabolism Protein kinase C Protein Kinase C - metabolism Signal Transduction
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