The excretion of biotrace elements using the multitracer technique in tumour-bearing mice

A radioactive multitracer solution obtained from the nuclear reaction of selenium with 25 MeV/nucleon 40Ar ions was used for investigation of trace element excretion into the faeces and urine of cancerous mice. The excretion rates of 22 elements (Na, K, Rb, Mg, Ca, Sr, Ga, As, Sc, V, Cr, Mn, Co, Fe,...

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Veröffentlicht in:Applied radiation and isotopes 2000-12, Vol.53 (6), p.969-974
Hauptverfasser: Wang, X., Tian, J., Yin, X.M., Zhang, X., Wang, Q.Z.
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creator Wang, X.
Tian, J.
Yin, X.M.
Zhang, X.
Wang, Q.Z.
description A radioactive multitracer solution obtained from the nuclear reaction of selenium with 25 MeV/nucleon 40Ar ions was used for investigation of trace element excretion into the faeces and urine of cancerous mice. The excretion rates of 22 elements (Na, K, Rb, Mg, Ca, Sr, Ga, As, Sc, V, Cr, Mn, Co, Fe, Y, Zr, Mo, Nb, Tc, Ru, Ag and In) were simultaneously measured under strictly identical experimental conditions, in order to clarify the excretion behavior of these elements in cancerous mice. The faecal and urinary excretion rates of Mg, Sr, Ga, As, Sc, V, Cr, Mn, Co, Fe, Y, Zr, Nb, Ru and Mo in cancerous mice, showed the in highest value at 0–8 hours. The accumulative excretion of Ca, Mo, Y and Zr was decreased and Na, Fe, Mn and Co increased in tumour-bearing mice, when compared to normal mice.
doi_str_mv 10.1016/S0969-8043(00)00105-6
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subjects Animals
Argon
Cancerous mice
Excretion
Faecal
Feces - chemistry
Male
Mice
Mice, Inbred BALB C
Multitracer
Neoplasms, Experimental - diagnostic imaging
Neoplasms, Experimental - metabolism
Neoplasms, Experimental - urine
Radioactive tracers
Radioisotopes
Radioisotopes - pharmacokinetics
Radioisotopes - urine
Radionuclide Imaging
Selenium
Trace analysis
Trace elements
Trace Elements - metabolism
Trace Elements - urine
Urine
title The excretion of biotrace elements using the multitracer technique in tumour-bearing mice
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