Therapeutic drug monitoring of HIV protease inhibitors using high-performance liquid chromatography with ultraviolet or photodiode array detection

Published data suggest that therapeutic drug monitoring of human immunodeficiency virus protease inhibitors would improve the management of antiretroviral therapy. The authors have developed a high-pressure liquid chromatographic assay allowing simultaneous determination of six protease inhibitors (...

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Veröffentlicht in:	Therapeutic drug monitoring 2001-12, Vol.23 (6), p.679-688
Hauptverfasser:	LEIBENGUTH, Patrice, LE GUELLEC, Chantal, BESNIER, Jean-Marc, BASTIDES, Frederic, MACE, Muriel, GAUDET, Marie-Laure, AUTRET-LECA, Elisabeth, PAINTAUD, Gilles
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Area Under Curve Biological and medical sciences Chromatography, High Pressure Liquid Cytochrome P-450 CYP3A Cytochrome P-450 Enzyme System - physiology Drug Monitoring General pharmacology HIV Protease Inhibitors - blood Humans Medical sciences Mixed Function Oxygenases - physiology Pharmacology. Drug treatments Sensitivity and Specificity
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