Effects of adenosine on extravascular lung water content in endotoxemic pigs

OBJECTIVE To investigate whether adenosine protects against endotoxin-induced increments in extravascular lung water content. DESIGN Prospective, randomized, animal study. SETTING University research laboratory. SUBJECTS Twenty-one anesthetized juvenile pigs. INTERVENTIONS The animals were divided i...

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Veröffentlicht in:	Critical care medicine 2001-12, Vol.29 (12), p.2371-2376
Hauptverfasser:	Kutzsche, Stefan, Lyberg, Torstein, Bjertnaes, Lars J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine - pharmacokinetics Adenosine - pharmacology Adenosine - therapeutic use Analysis of Variance Animals Biological and medical sciences Blood Pressure Capillary Permeability Endothelin-1 - blood Endotoxemia - drug therapy Escherichia coli Infections - drug therapy Extravascular Lung Water - drug effects Extravascular Lung Water - metabolism Hemodynamics Lung - blood supply Medical sciences Microcirculation Pharmacology. Drug treatments Pulmonary Gas Exchange Random Allocation Respiratory Distress Syndrome, Adult - drug therapy Respiratory system Swine Vasodilator Agents - pharmacokinetics Vasodilator Agents - pharmacology Vasodilator Agents - therapeutic use
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