Comparison of Novel and Existing Methods for Detection of Linkage Disequilibrium Using Parent‐Child Trios in the GAW12 Genetic Isolate Simulated Data

A novel method for joint detection of association caused by linkage disequilibrium (LD) and estimation of both recombination fraction and linkage disequilibrium parameters was compared to several existing implementations of the transmission/disequilibrium test (TDT) and modifications of the TDT in t...

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Veröffentlicht in:	Genetic epidemiology 2001, Vol.21 (S1), p.S378-S383
Hauptverfasser:	Bailey-Wilson, J.E., Sorant, A.J.M., Malley, J.D., Presciuttini, S., Redner, R.A., Severini, T.A., Badner, J.A., Pajevic, S., Jufer, R., Baffoe-Bonnie, A., Kao, L., Doan, B.Q., Goldstein, J.L., Holmes, T.N., Behneman, D., Mandal, D.M., Turley, T.N., Weissbecker, K.A., O'Neill, J., Pugh, E.W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analysis of Variance association Child Chromosome Mapping - statistics & numerical data ELAAT Female Genetic Markers - genetics Genetic Predisposition to Disease - genetics Genotype Humans Linkage Disequilibrium Lod Score Male Models, Genetic Polymorphism, Single Nucleotide power Quantitative Trait, Heritable TDT
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