Direct process integration of cell disruption and fluidised bed adsorption in the recovery of labile microbial enzymes

The practical feasibility and generic applicability of the direct integration of cell disruption by bead milling with the capture of intracellular products by fluidised bed adsorption has been demonstrated. Pilot-scale purification of the enzyme L-asparaginase from unclarified Erwinia chrysanthemi d...

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Veröffentlicht in:Bioseparation 2001, Vol.10 (1-3), p.73-85
Hauptverfasser: Bierau, H, Hinton, R J, Lyddiatt, A
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Sprache:eng
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