Endocytosis of Insulin-like Growth Factor II by a Mini-receptor Based on Repeat 11 of the Mannose 6-Phosphate/Insulin-like Growth Factor II Receptor

The mannose 6-phosphate/insulin-like growth factor II receptor (M6P/IGF-II receptor) plays an important role in controlling the extracellular level of the insulin-like growth factor II (IGF-II) by mediating its binding at the cell surface and delivery to lysosomes. Loss of the receptor is associated...

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Veröffentlicht in:	The Journal of biological chemistry 2000-10, Vol.275 (43), p.33697-33703
Hauptverfasser:	Grimme, Susanne, Höning, Stefan, von Figura, Kurt, Schmidt, Bernhard
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cricetinae Endocytosis Insulin-Like Growth Factor II - metabolism Mice Receptor, IGF Type 2 - chemistry Receptor, IGF Type 2 - metabolism Recombinant Proteins - metabolism Repetitive Sequences, Amino Acid
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