An Intronic Downstream Enhancer Promotes 3′ Splice Site Usage of a Neural Cell-specific Exon

The human nonmuscle myosin heavy chain B gene contains a 30-nucleotide alternative exon, N30, that is included in the mRNA from neural cells but is skipped in all other cells. We have previously identified an intronic distal downstream enhancer (IDDE) region that is required for neural cell-specific...

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Veröffentlicht in:	The Journal of biological chemistry 2000-10, Vol.275 (43), p.33641-33649
Hauptverfasser:	Guo, Neng-hua, Kawamoto, Sachiyo
Format:	Artikel
Sprache:	eng
Schlagworte:	Enhancer Elements, Genetic Exons Humans Myosin Heavy Chains - genetics RNA - metabolism RNA Precursors - metabolism RNA Splicing U2AF protein
Online-Zugang:	Volltext
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