T-Tropic Sequence of the V3 Loop Is Critical for HIV-1 Infection of CXCR4-Positive Colonic HT-29 Epithelial Cells

Some colonic and neuronal cells which are CD4 but galactosyl ceramidepositive are susceptible to infection with HIV-1. We have previously shown that the T-cell tropic V3 loop of HIV-1 gp120 serves as a primary viral determinant for infectivity of CD4 neuronal cells. However, the nature of the V3 loo...

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