Pilot study on the use of sublingual misoprostol for medical abortion
A new route of sublingual administration of misoprostol was used by 25 women with first trimester, non-viable intrauterine gestation and by 18 women requesting mid-trimester termination of pregnancy. Twenty-three women (92%, 95% CI 75, 98) with first trimester, non-viable gestation had complete abor...
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| Veröffentlicht in: | Contraception (Stoneham) 2001-11, Vol.64 (5), p.315-317 |
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| container_title | Contraception (Stoneham) |
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| creator | Tang, O.S. Ho, P.C. |
| description | A new route of sublingual administration of misoprostol was used by 25 women with first trimester, non-viable intrauterine gestation and by 18 women requesting mid-trimester termination of pregnancy. Twenty-three women (92%, 95% CI 75, 98) with first trimester, non-viable gestation had complete abortion after sublingual misoprostol. All women (100%, 95% CI 82, 100) requesting second trimester abortion aborted, and the median induction-to-abortion interval was 11.6 h. Our preliminary results on sublingual misoprostol show that it is a promising method for medical abortion. Prospective randomized studies are required to compare its efficacy and side effects with vaginal misoprostol and to work out the dosage and dosing interval. |
| doi_str_mv | 10.1016/S0010-7824(01)00261-X |
| format | Article |
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Therapeutic abortion</subject><subject>Medical abortion</subject><subject>Medical sciences</subject><subject>Misoprostol</subject><subject>Misoprostol - administration & dosage</subject><subject>Misoprostol - therapeutic use</subject><subject>Pilot Projects</subject><subject>Pregnancy</subject><subject>Sublingual</subject><subject>Treatment Outcome</subject><issn>0010-7824</issn><issn>1879-0518</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkF1LBCEUQCWK2j5-QuFLUQ9T13Ec16eIpS9YKKigN3HcaxmzY-lM0L_PbZd67EmUc_V4CNlncMqA1WcPAAwKOS6rY2AnAGXNiuc1MmJjqQoQbLxORr_IFtlO6Q0ApBJyk2wxJqWsFB-Ry3vfhp6mfph90dDR_hXpkJAGR9PQtL57GUxL5z6F9xhSH1rqQqRznHmbz00TYu9Dt0s2nGkT7q3WHfJ0dfk4uSmmd9e3k4tpYblifeGwUUaUDWZboWpTyaZG2UhXKSXQVFaYukTrwDRCAHCnXN4bW4O1vCo53yFHy3uzzMeAqdfZzGLbmg7DkLQs-bhWUmZQLEGbrVNEp9-jn5v4pRnoRT_9008v4mhg-qeffs5zB6sHhiZ_8m9qFSwDhyvApFzARdNZn_44XjGoOWTufMlhzvHpMepkPXY2h4toez0L_h-VbzYujRE</recordid><startdate>20011101</startdate><enddate>20011101</enddate><creator>Tang, O.S.</creator><creator>Ho, P.C.</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20011101</creationdate><title>Pilot study on the use of sublingual misoprostol for medical abortion</title><author>Tang, O.S. ; Ho, P.C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c391t-feb9a52be026596a47b6e7b7f4995ea4c5a62ecf0ab55003f9f62eac60cc34233</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Abortion, Induced - adverse effects</topic><topic>Administration, Sublingual</topic><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Birth control</topic><topic>Female</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Induced abortion. Therapeutic abortion</topic><topic>Medical abortion</topic><topic>Medical sciences</topic><topic>Misoprostol</topic><topic>Misoprostol - administration & dosage</topic><topic>Misoprostol - therapeutic use</topic><topic>Pilot Projects</topic><topic>Pregnancy</topic><topic>Sublingual</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tang, O.S.</creatorcontrib><creatorcontrib>Ho, P.C.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Contraception (Stoneham)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tang, O.S.</au><au>Ho, P.C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pilot study on the use of sublingual misoprostol for medical abortion</atitle><jtitle>Contraception (Stoneham)</jtitle><addtitle>Contraception</addtitle><date>2001-11-01</date><risdate>2001</risdate><volume>64</volume><issue>5</issue><spage>315</spage><epage>317</epage><pages>315-317</pages><issn>0010-7824</issn><eissn>1879-0518</eissn><coden>CCPTAY</coden><abstract>A new route of sublingual administration of misoprostol was used by 25 women with first trimester, non-viable intrauterine gestation and by 18 women requesting mid-trimester termination of pregnancy. Twenty-three women (92%, 95% CI 75, 98) with first trimester, non-viable gestation had complete abortion after sublingual misoprostol. All women (100%, 95% CI 82, 100) requesting second trimester abortion aborted, and the median induction-to-abortion interval was 11.6 h. Our preliminary results on sublingual misoprostol show that it is a promising method for medical abortion. Prospective randomized studies are required to compare its efficacy and side effects with vaginal misoprostol and to work out the dosage and dosing interval.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>11777493</pmid><doi>10.1016/S0010-7824(01)00261-X</doi><tpages>3</tpages></addata></record> |
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| ispartof | Contraception (Stoneham), 2001-11, Vol.64 (5), p.315-317 |
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Abortion, Induced - adverse effects Administration, Sublingual Adult Biological and medical sciences Birth control Female Gynecology. Andrology. Obstetrics Humans Induced abortion. Therapeutic abortion Medical abortion Medical sciences Misoprostol Misoprostol - administration & dosage Misoprostol - therapeutic use Pilot Projects Pregnancy Sublingual Treatment Outcome |
| title | Pilot study on the use of sublingual misoprostol for medical abortion |
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