The fanconi anemia protein FANCF forms a nuclear complex with FANCA, FANCC and FANCG

Fanconi anemia (FA) is a chromosomal instability syndrome associated with a strong predisposition to cancer, particularly acute myeloid leukemia and squamous cell carcinoma. At the cellular level, FA is characterized by spontaneous chromosomal breakage and a unique hypersensitivity to DNA cross-link...

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Veröffentlicht in:	Human molecular genetics 2000-11, Vol.9 (18), p.2665-2674
Hauptverfasser:	DE WINTER, Johan P, VAN DER WEEL, Laura, DE GROOT, Jan, STONE, Stacie, WAISFISZ, Quinten, ARWERT, Fré, SCHEPER, Rik J, KRUYT, Frank A. E, HOATLIN, Maureen E, JOENJE, Hans
Format:	Artikel
Sprache:	eng
Schlagworte:	Anemias. Hemoglobinopathies Antibody Specificity Biological and medical sciences Blotting, Western Cell Cycle Proteins Cell Nucleus - chemistry Cell Nucleus - metabolism Cytoplasm - chemistry Cytoplasm - metabolism Diseases of red blood cells DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism FANCA protein FANCC protein FANCF protein FANCG protein Fanconi Anemia - genetics Fanconi Anemia - metabolism Fanconi Anemia Complementation Group A Protein Fanconi Anemia Complementation Group C Protein Fanconi Anemia Complementation Group F Protein Fanconi Anemia Complementation Group G Protein Fanconi Anemia Complementation Group Proteins Genetic Complementation Test Hematologic and hematopoietic diseases Humans Lymphocytes - metabolism Lymphocytes - pathology Macromolecular Substances Medical sciences Models, Biological Nuclear Proteins - genetics Nuclear Proteins - metabolism Precipitin Tests Protein Binding Protein Biosynthesis Proteins - genetics Proteins - metabolism RNA-Binding Proteins - genetics RNA-Binding Proteins - metabolism
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