Increased Expression of Angiotensin- converting Enzyme in Retinas of Diabetic Rats

Purpose: The aim of this study was to examine the localization and the changes in the amount of angiotensin-converting enzyme (ACE) and the relationship between the renin-angiotensin (RA) system and vascular endothelial growth factor (VEGF)/VEGF-receptor system in the retinas of diabetic rats. Metho...

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Veröffentlicht in:	Japanese journal of ophthalmology 2001-11, Vol.45 (6), p.585-591
Hauptverfasser:	Okada, Yuji, Yamanaka, Ichiro, Sakamoto, Taiji, Hata, Yasuaki, Sassa, Yukio, Yoshikawa, Hiroshi, Fujisawa, Kimihiko, Ishibashi, Tatsuro, Inomata, Hajime
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin-converting enzyme Animals Diabetes Mellitus, Experimental - enzymology Diabetes Mellitus, Experimental - pathology diabetic retinopathy Diabetic Retinopathy - enzymology Diabetic Retinopathy - pathology Endothelial Growth Factors - metabolism Immunoenzyme Techniques Lymphokines - metabolism Peptidyl-Dipeptidase A - metabolism Rats Rats, Wistar Receptor Protein-Tyrosine Kinases - metabolism Receptors, Growth Factor - metabolism Receptors, Vascular Endothelial Growth Factor renin-angiotensin system Renin-Angiotensin System - physiology retinal vessels Retinal Vessels - enzymology Retinal Vessels - pathology streptozotocin Up-Regulation Vascular Endothelial Growth Factor A Vascular Endothelial Growth Factors
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