Dominant Right Ventricular Infarction: Is Angioplasty the Optimal Therapeutic Approach?
Approximately 30 % of all acute inferior myocardial infarctions (AIMI) are accompanied by acute right ventricular infarction (ARVI) as a consequence of proximal right coronary artery (RCA) occlusion. Fifty per cent of all patients with ARVI manifest hypotension, jugular venous distension, and dyspno...
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| Veröffentlicht in: | Acta medica Austriaca 2001-01, Vol.28 (5), p.129-134 |
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| creator | Pintarić, H. Nikolić‐Heitzler, V. Mihatov, Šime Vukosavić, D. Lukenda, J. Radić, B. Starčević, B. Žigman, M. Sharma, Mirella |
| description | Approximately 30 % of all acute inferior myocardial infarctions (AIMI) are accompanied by acute right ventricular infarction (ARVI) as a consequence of proximal right coronary artery (RCA) occlusion. Fifty per cent of all patients with ARVI manifest hypotension, jugular venous distension, and dyspnoea with clear lung fields, which is then considered as dominant acute RVI (ARVI). The inhospital mortality rate of patients with ARVI who are treated traditionally is very high. Thrombolytic therapy is relatively ineffective, while primary angioplasty is a more recent approach yet to be established as optimal treatment for patients with ARVI. Thirty‐eight patients with dominant ARVI were admitted to our CCU over a period of 24 months. The patients were retrospectively divided into 3 groups according to treatment: Group I (n = 16): traditional treatment; Group II (n = 12): thrombolytic therapy (streptokinase); Group III (n = 10): angioplasty after urgent coronarography. We tested the difference in the number of deaths in all groups by the Fisher exact test. There was a significant difference in the number of deaths between Group I and Group III (P |
| doi_str_mv | 10.1046/j.1563-2571.2001.01032.x |
| format | Article |
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Is Angioplasty the Optimal Therapeutic Approach?</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Pintarić, H. ; Nikolić‐Heitzler, V. ; Mihatov, Šime ; Vukosavić, D. ; Lukenda, J. ; Radić, B. ; Starčević, B. ; Žigman, M. ; Sharma, Mirella</creator><creatorcontrib>Pintarić, H. ; Nikolić‐Heitzler, V. ; Mihatov, Šime ; Vukosavić, D. ; Lukenda, J. ; Radić, B. ; Starčević, B. ; Žigman, M. ; Sharma, Mirella</creatorcontrib><description>Approximately 30 % of all acute inferior myocardial infarctions (AIMI) are accompanied by acute right ventricular infarction (ARVI) as a consequence of proximal right coronary artery (RCA) occlusion. Fifty per cent of all patients with ARVI manifest hypotension, jugular venous distension, and dyspnoea with clear lung fields, which is then considered as dominant acute RVI (ARVI). The inhospital mortality rate of patients with ARVI who are treated traditionally is very high. Thrombolytic therapy is relatively ineffective, while primary angioplasty is a more recent approach yet to be established as optimal treatment for patients with ARVI. Thirty‐eight patients with dominant ARVI were admitted to our CCU over a period of 24 months. The patients were retrospectively divided into 3 groups according to treatment: Group I (n = 16): traditional treatment; Group II (n = 12): thrombolytic therapy (streptokinase); Group III (n = 10): angioplasty after urgent coronarography. We tested the difference in the number of deaths in all groups by the Fisher exact test. There was a significant difference in the number of deaths between Group I and Group III (P < 0.05). Mortality reduction was also noted between Group II and Group III, which, however, proved to be statistically insignificant.
Zusammenfassung: Der Rechtsherzinfarkt ist in ungefähr 30 % aller diaphragmalen und/oder Hinterwandinfarktfällen eine Begleiterscheinung, die als Folge einer Okklusion des proximalen Segmentes der rechten Koronararterie vorkommt. In knapp 50 % aller Patienten mit Rechtsherzinfarkt präsentiert sich die Krankheit als dominanter Rechtsherzinfarkt; mit Hypotension, Halsvenenstauung und Dyspnoe, aber ohne verschattete Lungenfeldern. Die innenkrankenhäusliche Mortalität von Patienten, die traditionell behandelt wurden, ist sehr hoch. Die Lysetherapie ist ziemlich erfolglos, und die frühzeitige Koronarographie mit PTCA ist eine rezente Behandlungsmethode für Patienten mit Rechtsherzinfarkt, die gegenwärtig als optimal gelten dürfte.
In unserer kardiologischen Intensivstation wurden 38 Patienten mit dominantem akuten Rechtsherzinfarkt in einer Zeitspanne von 24 Monaten behandelt. Aufgrund der angewandten Therapie wurden sie in drei Gruppen aufgeteilt: Gruppe I (n = 16): traditionelle Therapie; Gruppe II (n = 12): Lysetherapie (Streptokinase); Gruppe III (n = 10): frühzeitige Koronarographie mit PTCA.
Wir haben den Mortalitätsunterschied zwischen allen Gruppen durch den Fischer‐Exakttest geprüft. Ein signifikanter Unterschied wurde zwischen den Gruppen I und III (P < 0,05) festgestellt. In der Gruppe III fanden wir eine niedrigere Mortalität als in der Gruppe II, der Unterschied jedoch war nicht statistisch signifikant.</description><identifier>ISSN: 0303-8173</identifier><identifier>EISSN: 1563-2571</identifier><identifier>DOI: 10.1046/j.1563-2571.2001.01032.x</identifier><identifier>PMID: 11774774</identifier><language>eng</language><publisher>Berlin: Blackwell Wissenschaftsverlag</publisher><subject>Angioplastik ; angioplasty ; Angioplasty, Balloon, Coronary ; Dominant right ventricular infarction ; Dominanter Rechtsherzinfarkt ; Heart Ventricles ; Humans ; mortality ; Myocardial Infarction - mortality ; Myocardial Infarction - therapy ; Sterblichkeit ; Survival Rate ; therapeutic approach ; therapeutischer Zutritt ; Thrombolytic Therapy ; Treatment Outcome</subject><ispartof>Acta medica Austriaca, 2001-01, Vol.28 (5), p.129-134</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3662-a1fbb3968f01d48f157f7c5b1dd6cad272a6e429cdf83602f736a41084def5073</citedby><cites>FETCH-LOGICAL-c3662-a1fbb3968f01d48f157f7c5b1dd6cad272a6e429cdf83602f736a41084def5073</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1411,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11774774$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pintarić, H.</creatorcontrib><creatorcontrib>Nikolić‐Heitzler, V.</creatorcontrib><creatorcontrib>Mihatov, Šime</creatorcontrib><creatorcontrib>Vukosavić, D.</creatorcontrib><creatorcontrib>Lukenda, J.</creatorcontrib><creatorcontrib>Radić, B.</creatorcontrib><creatorcontrib>Starčević, B.</creatorcontrib><creatorcontrib>Žigman, M.</creatorcontrib><creatorcontrib>Sharma, Mirella</creatorcontrib><title>Dominant Right Ventricular Infarction:
Is Angioplasty the Optimal Therapeutic Approach?</title><title>Acta medica Austriaca</title><addtitle>Acta Med Austriaca</addtitle><description>Approximately 30 % of all acute inferior myocardial infarctions (AIMI) are accompanied by acute right ventricular infarction (ARVI) as a consequence of proximal right coronary artery (RCA) occlusion. Fifty per cent of all patients with ARVI manifest hypotension, jugular venous distension, and dyspnoea with clear lung fields, which is then considered as dominant acute RVI (ARVI). The inhospital mortality rate of patients with ARVI who are treated traditionally is very high. Thrombolytic therapy is relatively ineffective, while primary angioplasty is a more recent approach yet to be established as optimal treatment for patients with ARVI. Thirty‐eight patients with dominant ARVI were admitted to our CCU over a period of 24 months. The patients were retrospectively divided into 3 groups according to treatment: Group I (n = 16): traditional treatment; Group II (n = 12): thrombolytic therapy (streptokinase); Group III (n = 10): angioplasty after urgent coronarography. We tested the difference in the number of deaths in all groups by the Fisher exact test. There was a significant difference in the number of deaths between Group I and Group III (P < 0.05). Mortality reduction was also noted between Group II and Group III, which, however, proved to be statistically insignificant.
Zusammenfassung: Der Rechtsherzinfarkt ist in ungefähr 30 % aller diaphragmalen und/oder Hinterwandinfarktfällen eine Begleiterscheinung, die als Folge einer Okklusion des proximalen Segmentes der rechten Koronararterie vorkommt. In knapp 50 % aller Patienten mit Rechtsherzinfarkt präsentiert sich die Krankheit als dominanter Rechtsherzinfarkt; mit Hypotension, Halsvenenstauung und Dyspnoe, aber ohne verschattete Lungenfeldern. Die innenkrankenhäusliche Mortalität von Patienten, die traditionell behandelt wurden, ist sehr hoch. Die Lysetherapie ist ziemlich erfolglos, und die frühzeitige Koronarographie mit PTCA ist eine rezente Behandlungsmethode für Patienten mit Rechtsherzinfarkt, die gegenwärtig als optimal gelten dürfte.
In unserer kardiologischen Intensivstation wurden 38 Patienten mit dominantem akuten Rechtsherzinfarkt in einer Zeitspanne von 24 Monaten behandelt. Aufgrund der angewandten Therapie wurden sie in drei Gruppen aufgeteilt: Gruppe I (n = 16): traditionelle Therapie; Gruppe II (n = 12): Lysetherapie (Streptokinase); Gruppe III (n = 10): frühzeitige Koronarographie mit PTCA.
Wir haben den Mortalitätsunterschied zwischen allen Gruppen durch den Fischer‐Exakttest geprüft. Ein signifikanter Unterschied wurde zwischen den Gruppen I und III (P < 0,05) festgestellt. In der Gruppe III fanden wir eine niedrigere Mortalität als in der Gruppe II, der Unterschied jedoch war nicht statistisch signifikant.</description><subject>Angioplastik</subject><subject>angioplasty</subject><subject>Angioplasty, Balloon, Coronary</subject><subject>Dominant right ventricular infarction</subject><subject>Dominanter Rechtsherzinfarkt</subject><subject>Heart Ventricles</subject><subject>Humans</subject><subject>mortality</subject><subject>Myocardial Infarction - mortality</subject><subject>Myocardial Infarction - therapy</subject><subject>Sterblichkeit</subject><subject>Survival Rate</subject><subject>therapeutic approach</subject><subject>therapeutischer Zutritt</subject><subject>Thrombolytic Therapy</subject><subject>Treatment Outcome</subject><issn>0303-8173</issn><issn>1563-2571</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkMtKxDAUQIMoOj5-QbJy15pXk-pCKT4HRgZEXbgJmTRxMnTamqTo7Pwcv8svseMMuhUu3Av33AcHAIhRihHjx7MUZ5wmJBM4JQjhFGFESfq-AQa_jU0wQBTRJMeC7oDdEGY9SAQj22AHYyFYHwPwfNnMXa3qCO_dyzTCJ1NH73RXKQ-HtVVeR9fUp_Dr43MYYFG_uKatVIgLGKcGjtvo5qqCD1PjVWu66DQs2tY3Sk_P98GWVVUwB-u8Bx6vrx4ubpPR-GZ4UYwSTTknicJ2MqEnPLcIlyy3OBNW6GyCy5JrVRJBFDeMnOjS5pQjYgXlimGUs9LYDAm6B45We_u7r50JUc5d0KaqVG2aLkhBqMgJYz2Yr0DtmxC8sbL1_ft-ITGSS69yJpf65FKfXHqVP17lez96uL7RTeam_Btci-yBsxXw5iqz-PdiWdwVPyX9Bm6mh_E</recordid><startdate>20010101</startdate><enddate>20010101</enddate><creator>Pintarić, H.</creator><creator>Nikolić‐Heitzler, V.</creator><creator>Mihatov, Šime</creator><creator>Vukosavić, D.</creator><creator>Lukenda, J.</creator><creator>Radić, B.</creator><creator>Starčević, B.</creator><creator>Žigman, M.</creator><creator>Sharma, Mirella</creator><general>Blackwell Wissenschaftsverlag</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20010101</creationdate><title>Dominant Right Ventricular Infarction:
Is Angioplasty the Optimal Therapeutic Approach?</title><author>Pintarić, H. ; Nikolić‐Heitzler, V. ; Mihatov, Šime ; Vukosavić, D. ; Lukenda, J. ; Radić, B. ; Starčević, B. ; Žigman, M. ; Sharma, Mirella</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3662-a1fbb3968f01d48f157f7c5b1dd6cad272a6e429cdf83602f736a41084def5073</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Angioplastik</topic><topic>angioplasty</topic><topic>Angioplasty, Balloon, Coronary</topic><topic>Dominant right ventricular infarction</topic><topic>Dominanter Rechtsherzinfarkt</topic><topic>Heart Ventricles</topic><topic>Humans</topic><topic>mortality</topic><topic>Myocardial Infarction - mortality</topic><topic>Myocardial Infarction - therapy</topic><topic>Sterblichkeit</topic><topic>Survival Rate</topic><topic>therapeutic approach</topic><topic>therapeutischer Zutritt</topic><topic>Thrombolytic Therapy</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pintarić, H.</creatorcontrib><creatorcontrib>Nikolić‐Heitzler, V.</creatorcontrib><creatorcontrib>Mihatov, Šime</creatorcontrib><creatorcontrib>Vukosavić, D.</creatorcontrib><creatorcontrib>Lukenda, J.</creatorcontrib><creatorcontrib>Radić, B.</creatorcontrib><creatorcontrib>Starčević, B.</creatorcontrib><creatorcontrib>Žigman, M.</creatorcontrib><creatorcontrib>Sharma, Mirella</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Acta medica Austriaca</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pintarić, H.</au><au>Nikolić‐Heitzler, V.</au><au>Mihatov, Šime</au><au>Vukosavić, D.</au><au>Lukenda, J.</au><au>Radić, B.</au><au>Starčević, B.</au><au>Žigman, M.</au><au>Sharma, Mirella</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dominant Right Ventricular Infarction:
Is Angioplasty the Optimal Therapeutic Approach?</atitle><jtitle>Acta medica Austriaca</jtitle><addtitle>Acta Med Austriaca</addtitle><date>2001-01-01</date><risdate>2001</risdate><volume>28</volume><issue>5</issue><spage>129</spage><epage>134</epage><pages>129-134</pages><issn>0303-8173</issn><eissn>1563-2571</eissn><abstract>Approximately 30 % of all acute inferior myocardial infarctions (AIMI) are accompanied by acute right ventricular infarction (ARVI) as a consequence of proximal right coronary artery (RCA) occlusion. Fifty per cent of all patients with ARVI manifest hypotension, jugular venous distension, and dyspnoea with clear lung fields, which is then considered as dominant acute RVI (ARVI). The inhospital mortality rate of patients with ARVI who are treated traditionally is very high. Thrombolytic therapy is relatively ineffective, while primary angioplasty is a more recent approach yet to be established as optimal treatment for patients with ARVI. Thirty‐eight patients with dominant ARVI were admitted to our CCU over a period of 24 months. The patients were retrospectively divided into 3 groups according to treatment: Group I (n = 16): traditional treatment; Group II (n = 12): thrombolytic therapy (streptokinase); Group III (n = 10): angioplasty after urgent coronarography. We tested the difference in the number of deaths in all groups by the Fisher exact test. There was a significant difference in the number of deaths between Group I and Group III (P < 0.05). Mortality reduction was also noted between Group II and Group III, which, however, proved to be statistically insignificant.
Zusammenfassung: Der Rechtsherzinfarkt ist in ungefähr 30 % aller diaphragmalen und/oder Hinterwandinfarktfällen eine Begleiterscheinung, die als Folge einer Okklusion des proximalen Segmentes der rechten Koronararterie vorkommt. In knapp 50 % aller Patienten mit Rechtsherzinfarkt präsentiert sich die Krankheit als dominanter Rechtsherzinfarkt; mit Hypotension, Halsvenenstauung und Dyspnoe, aber ohne verschattete Lungenfeldern. Die innenkrankenhäusliche Mortalität von Patienten, die traditionell behandelt wurden, ist sehr hoch. Die Lysetherapie ist ziemlich erfolglos, und die frühzeitige Koronarographie mit PTCA ist eine rezente Behandlungsmethode für Patienten mit Rechtsherzinfarkt, die gegenwärtig als optimal gelten dürfte.
In unserer kardiologischen Intensivstation wurden 38 Patienten mit dominantem akuten Rechtsherzinfarkt in einer Zeitspanne von 24 Monaten behandelt. Aufgrund der angewandten Therapie wurden sie in drei Gruppen aufgeteilt: Gruppe I (n = 16): traditionelle Therapie; Gruppe II (n = 12): Lysetherapie (Streptokinase); Gruppe III (n = 10): frühzeitige Koronarographie mit PTCA.
Wir haben den Mortalitätsunterschied zwischen allen Gruppen durch den Fischer‐Exakttest geprüft. Ein signifikanter Unterschied wurde zwischen den Gruppen I und III (P < 0,05) festgestellt. In der Gruppe III fanden wir eine niedrigere Mortalität als in der Gruppe II, der Unterschied jedoch war nicht statistisch signifikant.</abstract><cop>Berlin</cop><pub>Blackwell Wissenschaftsverlag</pub><pmid>11774774</pmid><doi>10.1046/j.1563-2571.2001.01032.x</doi><tpages>6</tpages></addata></record> |
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| subjects | Angioplastik angioplasty Angioplasty, Balloon, Coronary Dominant right ventricular infarction Dominanter Rechtsherzinfarkt Heart Ventricles Humans mortality Myocardial Infarction - mortality Myocardial Infarction - therapy Sterblichkeit Survival Rate therapeutic approach therapeutischer Zutritt Thrombolytic Therapy Treatment Outcome |
| title | Dominant Right Ventricular Infarction:
Is Angioplasty the Optimal Therapeutic Approach? |
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