Protective effect and mechanism of Ginkgo biloba leaf extracts for Parkinson disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

To observe the effects of extracts of Ginkgo biloba leaves (EGb) on the Parkinson disease (PD) models induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and its ion 1-methyl-4-phenylpyridinium (MPP+). MPTP was microinjected into substantia nigra of rats to induce a behavior change of rot...

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Veröffentlicht in:	Acta pharmacologica Sinica 2001-12, Vol.22 (12), p.1089-1093
Hauptverfasser:	Yang, S F, Wu, Q, Sun, A S, Huang, X N, Shi, J S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antiparkinson Agents - pharmacology Antiparkinson Agents - therapeutic use Apoptosis Drugs, Chinese Herbal - pharmacology Drugs, Chinese Herbal - therapeutic use Female Ginkgo biloba - chemistry Male Neurons - pathology Parkinsonian Disorders - blood Parkinsonian Disorders - pathology Parkinsonian Disorders - prevention & control PC12 Cells - pathology Plant Leaves - chemistry Random Allocation Rats Substantia Nigra - physiology Superoxide Dismutase - blood
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