Immune control of Brucella abortus 2308 infections in BALB/c mice

Abstract BALB/c mice infected with Brucella abortus strain 2308 have 10-fold higher levels of bacteria during the plateau phase of infection (the time period when the number of colony-forming units in vivo remains consistent) than the more resistant C57BL/10 mice. This is due to a cessation of inter...

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Veröffentlicht in:	FEMS immunology and medical microbiology 2001-12, Vol.32 (1), p.85-88
Hauptverfasser:	Murphy, Erin A., Parent, Michelle, Sathiyaseelan, Janaki, Jiang, Xiaosui, Baldwin, Cynthia L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacteria Biological and medical sciences Brucella abortus Brucella abortus - immunology Brucella abortus - pathogenicity Brucellosis - immunology CD8 antigen CD8 T cell CD8-Positive T-Lymphocytes - immunology Colonies Depletion Fundamental and applied biological sciences. Psychology Infections Interferon Leukocytes (neutrophilic) Lymphocytes Lymphocytes T Macrophages Mice Mice, Inbred BALB C Microbiology Monoclonal antibodies Neutralization Rodents Spleen Spleen - cytology Spleen - immunology Tumor Necrosis Factor-alpha - metabolism Tumor necrosis factor-TNF Tumor necrosis factor-α γ-Interferon
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