STR primer concordance study
Over 1500 population database samples comprising African Americans, Caucasians, Hispanics, Native Americans, Chamorros and Filipinos were typed using the PowerPlex® 16 and the Profiler Plus™/COfiler™ kits. Except for the D8S1179 locus in Chamorros and Filipinos from Guam, there were eight examples i...
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| Veröffentlicht in: | Forensic science international 2001-12, Vol.124 (1), p.47-54 |
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| creator | Budowle, Bruce Masibay, Arni Anderson, Stacey J. Barna, Charles Biega, Lisa Brenneke, Susanne Brown, Barry L. Cramer, Jill DeGroot, Gretchen A. Douglas, Derek Duceman, Barry Eastman, Allison Giles, Robert Hamill, Jennifer Haase, Daniel J. Janssen, Dirk W. Kupferschmid, Timothy D. Lawton, Terry Lemire, Christine Llewellyn, Barbara Moretti, Tamyra Neves, Jennifer Palaski, Chris Schueler, Sindey Sgueglia, Joanne Sprecher, Cynthia Tomsey, Christine Yet, Don |
| description | Over 1500 population database samples comprising African Americans, Caucasians, Hispanics, Native Americans, Chamorros and Filipinos were typed using the PowerPlex® 16 and the Profiler Plus™/COfiler™ kits. Except for the D8S1179 locus in Chamorros and Filipinos from Guam, there were eight examples in which a typing difference due to allele dropout was observed. At the D8S1179 locus in the population samples from Guam, there were 13 examples of allele dropout observed when using the Profiler Plus kit. The data support that the primers used in the PowerPlex® 16, Profiler Plus™, and COfiler™ kits are reliable for typing reference samples that are for use in CODIS. In addition, allele frequency databases have been established for the STR loci Penta D and Penta E. Both loci are highly polymorphic. |
| doi_str_mv | 10.1016/S0379-0738(01)00563-1 |
| format | Article |
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Except for the D8S1179 locus in Chamorros and Filipinos from Guam, there were eight examples in which a typing difference due to allele dropout was observed. At the D8S1179 locus in the population samples from Guam, there were 13 examples of allele dropout observed when using the Profiler Plus kit. The data support that the primers used in the PowerPlex® 16, Profiler Plus™, and COfiler™ kits are reliable for typing reference samples that are for use in CODIS. In addition, allele frequency databases have been established for the STR loci Penta D and Penta E. Both loci are highly polymorphic.</description><identifier>ISSN: 0379-0738</identifier><identifier>EISSN: 1872-6283</identifier><identifier>DOI: 10.1016/S0379-0738(01)00563-1</identifier><identifier>PMID: 11741760</identifier><identifier>CODEN: FSINDR</identifier><language>eng</language><publisher>Kidlington: Elsevier B.V</publisher><subject>African Americans ; Allele dropout ; Alleles ; AmpFlSTR® COfiler™ kit ; AmpFlSTR® Profiler Plus™ kit ; Binding sites ; Biological and medical sciences ; CODIS ; Concordance ; Continental Population Groups - genetics ; Databases, Factual ; Deoxyribonucleic acid ; Diverse techniques ; DNA ; Forensic Medicine ; Forensic sciences ; Fundamental and applied biological sciences. Psychology ; Gene frequency ; Genetic testing ; Genetics, Population ; Hardy–Weinberg expectations ; Humans ; Laboratories ; Loci ; Minority & ethnic groups ; Molecular and cellular biology ; Native Americans ; Penta D ; Penta E ; Population ; Population genetics ; Population studies ; PowerPlex® 16 kit ; PowerPlex® 2.1 kit ; Primers ; single tandem repeats ; Stochastic effects ; STR ; Tandem Repeat Sequences ; Typing ; United States</subject><ispartof>Forensic science international, 2001-12, Vol.124 (1), p.47-54</ispartof><rights>2001 Elsevier Science Ireland Ltd</rights><rights>2002 INIST-CNRS</rights><rights>2001. Elsevier Science Ireland Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c450t-8ee342e506070068eb2b952bb5a2f81b45a0d8d3c0356caf355cd994d93233383</citedby><cites>FETCH-LOGICAL-c450t-8ee342e506070068eb2b952bb5a2f81b45a0d8d3c0356caf355cd994d93233383</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/2188915665?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995,64385,64387,64389,72469</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=13393974$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11741760$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Budowle, Bruce</creatorcontrib><creatorcontrib>Masibay, Arni</creatorcontrib><creatorcontrib>Anderson, Stacey J.</creatorcontrib><creatorcontrib>Barna, Charles</creatorcontrib><creatorcontrib>Biega, Lisa</creatorcontrib><creatorcontrib>Brenneke, Susanne</creatorcontrib><creatorcontrib>Brown, Barry L.</creatorcontrib><creatorcontrib>Cramer, Jill</creatorcontrib><creatorcontrib>DeGroot, Gretchen A.</creatorcontrib><creatorcontrib>Douglas, Derek</creatorcontrib><creatorcontrib>Duceman, Barry</creatorcontrib><creatorcontrib>Eastman, Allison</creatorcontrib><creatorcontrib>Giles, Robert</creatorcontrib><creatorcontrib>Hamill, Jennifer</creatorcontrib><creatorcontrib>Haase, Daniel J.</creatorcontrib><creatorcontrib>Janssen, Dirk W.</creatorcontrib><creatorcontrib>Kupferschmid, Timothy D.</creatorcontrib><creatorcontrib>Lawton, Terry</creatorcontrib><creatorcontrib>Lemire, Christine</creatorcontrib><creatorcontrib>Llewellyn, Barbara</creatorcontrib><creatorcontrib>Moretti, Tamyra</creatorcontrib><creatorcontrib>Neves, Jennifer</creatorcontrib><creatorcontrib>Palaski, Chris</creatorcontrib><creatorcontrib>Schueler, Sindey</creatorcontrib><creatorcontrib>Sgueglia, Joanne</creatorcontrib><creatorcontrib>Sprecher, Cynthia</creatorcontrib><creatorcontrib>Tomsey, Christine</creatorcontrib><creatorcontrib>Yet, Don</creatorcontrib><title>STR primer concordance study</title><title>Forensic science international</title><addtitle>Forensic Sci Int</addtitle><description>Over 1500 population database samples comprising African Americans, Caucasians, Hispanics, Native Americans, Chamorros and Filipinos were typed using the PowerPlex® 16 and the Profiler Plus™/COfiler™ kits. Except for the D8S1179 locus in Chamorros and Filipinos from Guam, there were eight examples in which a typing difference due to allele dropout was observed. At the D8S1179 locus in the population samples from Guam, there were 13 examples of allele dropout observed when using the Profiler Plus kit. The data support that the primers used in the PowerPlex® 16, Profiler Plus™, and COfiler™ kits are reliable for typing reference samples that are for use in CODIS. In addition, allele frequency databases have been established for the STR loci Penta D and Penta E. Both loci are highly polymorphic.</description><subject>African Americans</subject><subject>Allele dropout</subject><subject>Alleles</subject><subject>AmpFlSTR® COfiler™ kit</subject><subject>AmpFlSTR® Profiler Plus™ kit</subject><subject>Binding sites</subject><subject>Biological and medical sciences</subject><subject>CODIS</subject><subject>Concordance</subject><subject>Continental Population Groups - genetics</subject><subject>Databases, Factual</subject><subject>Deoxyribonucleic acid</subject><subject>Diverse techniques</subject><subject>DNA</subject><subject>Forensic Medicine</subject><subject>Forensic sciences</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Gene frequency</subject><subject>Genetic testing</subject><subject>Genetics, Population</subject><subject>Hardy–Weinberg expectations</subject><subject>Humans</subject><subject>Laboratories</subject><subject>Loci</subject><subject>Minority & ethnic groups</subject><subject>Molecular and cellular biology</subject><subject>Native Americans</subject><subject>Penta D</subject><subject>Penta E</subject><subject>Population</subject><subject>Population genetics</subject><subject>Population studies</subject><subject>PowerPlex® 16 kit</subject><subject>PowerPlex® 2.1 kit</subject><subject>Primers</subject><subject>single tandem repeats</subject><subject>Stochastic effects</subject><subject>STR</subject><subject>Tandem Repeat Sequences</subject><subject>Typing</subject><subject>United States</subject><issn>0379-0738</issn><issn>1872-6283</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqF0EtLAzEQwPEgitbHN1ApiKKH1ZnM5rEnEfEFBcHqOWSTLKy0XU26gt_e1BYFL55y-c0w-TN2gHCOgPJiDKSqAhTpU8AzACGpwDU2QK14IbmmdTb4IVtsO6VXyEpwucm2EFWJSsKA7Y-fn4ZvsZ2GOHTdzHXR25kLwzTv_ecu22jsJIW91bvDXm5vnq_vi9Hj3cP11ahwpYB5oUOgkgcBEhSA1KHmdSV4XQvLG411KSx47ckBCelsQ0I4X1Wlr4gTkaYddrLc-xa79z6kuZm2yYXJxM5C1yejOEkNWv4LURMCVyLDoz_wtevjLH_CcNS6QiHlQomlcrFLKYbGLErY-GkQzKKy-a5sFgkNoPmubDDPHa629_U0-N-pVdYMjlfAJmcnTcxN2_TriCqqVJnd5dKFXPejDdEk14bc37cxuLnxXfvPKV-wsJTs</recordid><startdate>20011215</startdate><enddate>20011215</enddate><creator>Budowle, Bruce</creator><creator>Masibay, Arni</creator><creator>Anderson, Stacey J.</creator><creator>Barna, Charles</creator><creator>Biega, Lisa</creator><creator>Brenneke, Susanne</creator><creator>Brown, Barry L.</creator><creator>Cramer, Jill</creator><creator>DeGroot, Gretchen A.</creator><creator>Douglas, Derek</creator><creator>Duceman, Barry</creator><creator>Eastman, Allison</creator><creator>Giles, Robert</creator><creator>Hamill, Jennifer</creator><creator>Haase, Daniel J.</creator><creator>Janssen, Dirk W.</creator><creator>Kupferschmid, Timothy D.</creator><creator>Lawton, Terry</creator><creator>Lemire, Christine</creator><creator>Llewellyn, Barbara</creator><creator>Moretti, Tamyra</creator><creator>Neves, Jennifer</creator><creator>Palaski, Chris</creator><creator>Schueler, Sindey</creator><creator>Sgueglia, Joanne</creator><creator>Sprecher, Cynthia</creator><creator>Tomsey, Christine</creator><creator>Yet, Don</creator><general>Elsevier B.V</general><general>Elsevier</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7U7</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>20011215</creationdate><title>STR primer concordance study</title><author>Budowle, Bruce ; Masibay, Arni ; Anderson, Stacey J. ; Barna, Charles ; Biega, Lisa ; Brenneke, Susanne ; Brown, Barry L. ; Cramer, Jill ; DeGroot, Gretchen A. ; Douglas, Derek ; Duceman, Barry ; Eastman, Allison ; Giles, Robert ; Hamill, Jennifer ; Haase, Daniel J. ; Janssen, Dirk W. ; Kupferschmid, Timothy D. ; Lawton, Terry ; Lemire, Christine ; Llewellyn, Barbara ; Moretti, Tamyra ; Neves, Jennifer ; Palaski, Chris ; Schueler, Sindey ; Sgueglia, Joanne ; Sprecher, Cynthia ; Tomsey, Christine ; Yet, Don</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c450t-8ee342e506070068eb2b952bb5a2f81b45a0d8d3c0356caf355cd994d93233383</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>African Americans</topic><topic>Allele dropout</topic><topic>Alleles</topic><topic>AmpFlSTR® COfiler™ kit</topic><topic>AmpFlSTR® Profiler Plus™ kit</topic><topic>Binding sites</topic><topic>Biological and medical sciences</topic><topic>CODIS</topic><topic>Concordance</topic><topic>Continental Population Groups - genetics</topic><topic>Databases, Factual</topic><topic>Deoxyribonucleic acid</topic><topic>Diverse techniques</topic><topic>DNA</topic><topic>Forensic Medicine</topic><topic>Forensic sciences</topic><topic>Fundamental and applied biological sciences. 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Except for the D8S1179 locus in Chamorros and Filipinos from Guam, there were eight examples in which a typing difference due to allele dropout was observed. At the D8S1179 locus in the population samples from Guam, there were 13 examples of allele dropout observed when using the Profiler Plus kit. The data support that the primers used in the PowerPlex® 16, Profiler Plus™, and COfiler™ kits are reliable for typing reference samples that are for use in CODIS. In addition, allele frequency databases have been established for the STR loci Penta D and Penta E. Both loci are highly polymorphic.</abstract><cop>Kidlington</cop><pub>Elsevier B.V</pub><pmid>11741760</pmid><doi>10.1016/S0379-0738(01)00563-1</doi><tpages>8</tpages></addata></record> |
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| identifier | ISSN: 0379-0738 |
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| language | eng |
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| source | MEDLINE; Access via ScienceDirect (Elsevier); ProQuest Central UK/Ireland |
| subjects | African Americans Allele dropout Alleles AmpFlSTR® COfiler™ kit AmpFlSTR® Profiler Plus™ kit Binding sites Biological and medical sciences CODIS Concordance Continental Population Groups - genetics Databases, Factual Deoxyribonucleic acid Diverse techniques DNA Forensic Medicine Forensic sciences Fundamental and applied biological sciences. Psychology Gene frequency Genetic testing Genetics, Population Hardy–Weinberg expectations Humans Laboratories Loci Minority & ethnic groups Molecular and cellular biology Native Americans Penta D Penta E Population Population genetics Population studies PowerPlex® 16 kit PowerPlex® 2.1 kit Primers single tandem repeats Stochastic effects STR Tandem Repeat Sequences Typing United States |
| title | STR primer concordance study |
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