Tissue Microarray Analysis of β-Catenin in Colorectal Cancer Shows Nuclear Phospho-β-catenin Is Associated with a Better Prognosis

Purpose : β-Catenin is involved in homotypic cell-cell adhesion and the wnt signaling pathway. Deregulation of β-catenin levels, caused in part by mutations of the adenomatous polyposis coli gene, is thought to play a role in the development of colorectal and other cancers. To further elucidate thei...

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