unc-83 encodes a novel component of the nuclear envelope and is essential for proper nuclear migration

Nuclear migration plays an essential role in the growth and development of a wide variety of eukaryotes. Mutations in unc-84, which encodes a conserved component of the nuclear envelope, have been shown to disrupt nuclear migration in two C. elegans tissues. We show that mutations in unc-83 disrupt...

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Veröffentlicht in:	Development (Cambridge) 2001-12, Vol.128 (24), p.5039-5050
Hauptverfasser:	Starr, D A, Hermann, G J, Malone, C J, Fixsen, W, Priess, J R, Horvitz, H R, Han, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Active Transport, Cell Nucleus Animals Caenorhabditis elegans Caenorhabditis elegans Proteins Cell Compartmentation Cell Nucleus - physiology Centrosome - physiology centrosomes Cloning, Molecular Intestines - embryology Membrane Glycoproteins - isolation & purification Membrane Proteins - genetics Membrane Proteins - isolation & purification Microtubules - physiology Movement - physiology Nuclear Envelope - chemistry Nuclear Envelope - physiology Nuclear Matrix - physiology Nuclear Proteins - genetics Nuclear Proteins - isolation & purification RNA, Antisense RNA, Small Interfering UNC-83 protein unc-84 gene UNC-84 protein
Online-Zugang:	Volltext
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