Directing proteins to mitochondria by fusion to mitochondrial targeting signals

Specific targeting mechanisms have been identified for the various subcellular compartments in eukaryotic cells. These processes are mediated by dedicated translocation machineries. Most mitochondrial proteins are synthesized in the cytosol as larger precursors carrying a positively charged, N-termi...

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Veröffentlicht in:	Methods in Enzymology 2000, Vol.327, p.305-317
1. Verfasser:	Tokatlidis, Kostas
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry - methods Cytosol - metabolism Mitochondria - chemistry Mitochondria - metabolism Protein Biosynthesis Protein Transport Rabbits Recombinant Fusion Proteins - metabolism Reticulocytes - metabolism Saccharomyces cerevisiae - chemistry Saccharomyces cerevisiae - metabolism Signal Transduction
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