Vaginal Mucosa Serves as an Inductive Site for Tolerance

These data demonstrate that tolerance can be induced by vaginal Ag exposure. In these experiments, mice were given vaginal agarose gel suppositories containing either 5 mg OVA or saline for 6 h. Mice were given suppositories either during the estrous (estrogen dominant) or diestrous (progesterone do...

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Veröffentlicht in:	The Journal of immunology (1950) 2000-11, Vol.165 (9), p.5077-5083
Hauptverfasser:	Black, C. Allen, Rohan, Lisa C, Cost, Marilyn, Watkins, Simon C, Draviam, Romesh, Alber, Sean, Edwards, Robert P
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intravaginal Animals Antibody Formation - immunology Antigens - administration & dosage Antigens - immunology Antigens - metabolism Biological Transport - immunology Diffusion Estrus - immunology Female Immune Tolerance - immunology Immunity, Cellular - immunology Immunity, Mucosal Lymph Nodes - immunology Lymph Nodes - metabolism Mice Mice, Inbred C3H Ovalbumin - administration & dosage Ovalbumin - immunology Ovalbumin - metabolism Pessaries Sepharose - immunology Sepharose - metabolism Uterus - immunology Uterus - metabolism Vagina - immunology Vagina - metabolism Vaginal Creams, Foams, and Jellies
Online-Zugang:	Volltext
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