Differential gene expression in premalignant human trophoblast: Role of IGFBP‐5

Tumorigenesis results from genetic alterations that occur in a stepwise manner giving rise to cells with increasingly cancer‐like characteristics. We used in vitro propagated first trimester human extravillous trophoblast (EVT) cells to identify genetic changes responsible for the transition of the...

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Veröffentlicht in:	International journal of cancer 2001-12, Vol.94 (5), p.674-684
Hauptverfasser:	Lee, Boris P.‐L., Rushlow, Walter J., Chakraborty, Chandan, Lala, Peeyush K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Cell Line Cell Movement - drug effects differential display Female fibronectin Fibronectins - physiology Gene Expression Humans Insulin-Like Growth Factor Binding Protein 5 - genetics Insulin-Like Growth Factor Binding Protein 5 - physiology Insulin-Like Growth Factor II - pharmacology insulin‐like growth factor binding protein‐5 Molecular Sequence Data Neoplasm Invasiveness Precancerous Conditions - genetics Pregnancy RNA, Messenger - analysis trophoblast Trophoblastic Neoplasms - genetics tumor progression
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