Ethanol Exposure Enhances Apoptosis Within the Testes

Background: Chronic ethanol abuse causes testicular atrophy and male infertility in alcoholic men. It is well known that ethanol exposure disrupts the hypothalamic‐pituitary‐gonadal axis, adversely affects the secretory function of Sertoli cells, and produces oxidative stress within the testes. It i...

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Veröffentlicht in:	Alcoholism, clinical and experimental research clinical and experimental research, 2000-10, Vol.24 (10), p.1550-1556
Hauptverfasser:	Zhu, Qianlong, Meisinger, Jeremy, Emanuele, Nicholas V., Emanuele, Mary Ann, LaPaglia, Nancy, Van Thiel, David H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcoholism and acute alcohol poisoning Animals Apoptosis Apoptosis - drug effects bcl-2-Associated X Protein Biological and medical sciences Blotting, Western Cells, Cultured DNA Fragmentation Ethanol Ethanol - administration & dosage Ethanol - pharmacology Fas Ligand Protein fas Receptor - analysis Gene Expression Regulation - drug effects Genes, p53 - genetics Germ Cells In Situ Nick-End Labeling Injections Male Medical sciences Membrane Glycoproteins - analysis Proto-Oncogene Proteins - analysis Proto-Oncogene Proteins c-bcl-2 Rats Rats, Sprague-Dawley Reverse Transcriptase Polymerase Chain Reaction Testes Testis - chemistry Testis - cytology Testis - drug effects Toxicology
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